UNLABELLED: BACKGROUND AND RATIONALE FOR THE STUDY: Hepatitis B (HB) is one of the most prevalent occupational infections in health attendance environments. According to the Brazil Ministry of Health, health professionals must be vaccinated against the hepatitis B virus (HBV) and provide laboratory proof of immunization. AIMS: To evaluate the seroprevalence of HBV infection and to analyze the response to vaccine by measuring serum antibodies against HBV surface antigen (anti-HBs) levels in a sample of students and health professionals at the Federal University of Bahia. RESULTS: As part of this cross-sectional study, a campaign against occupational HB was launched in 2007 and vaccination and blood samples were collected for analysis of the following serological markers: HBV surface antigen (HBsAg) and anti-HBs (measured by enzyme-linked immunoassay) and total antibodies against HBV core antigen (anti-HBc). The study sample comprised 766 people. Global seropositivity for HBV was 1.7%: 0.5% in the students and 8.8% in the professionals. In a group of volunteers, a serological profile compatible with postvaccine immunity was shown by 95% of volunteers with proof of vaccination and by 81.8% of volunteers without proof of vaccination. CONCLUSIONS: In conclusion, this study shows that it is important to promote vaccination campaigns and improve knowledge and awareness about HB among health care workers and higher education students.
UNLABELLED: BACKGROUND AND RATIONALE FOR THE STUDY: Hepatitis B (HB) is one of the most prevalent occupational infections in health attendance environments. According to the Brazil Ministry of Health, health professionals must be vaccinated against the hepatitis B virus (HBV) and provide laboratory proof of immunization. AIMS: To evaluate the seroprevalence of HBV infection and to analyze the response to vaccine by measuring serum antibodies against HBV surface antigen (anti-HBs) levels in a sample of students and health professionals at the Federal University of Bahia. RESULTS: As part of this cross-sectional study, a campaign against occupational HB was launched in 2007 and vaccination and blood samples were collected for analysis of the following serological markers: HBV surface antigen (HBsAg) and anti-HBs (measured by enzyme-linked immunoassay) and total antibodies against HBV core antigen (anti-HBc). The study sample comprised 766 people. Global seropositivity for HBV was 1.7%: 0.5% in the students and 8.8% in the professionals. In a group of volunteers, a serological profile compatible with postvaccine immunity was shown by 95% of volunteers with proof of vaccination and by 81.8% of volunteers without proof of vaccination. CONCLUSIONS: In conclusion, this study shows that it is important to promote vaccination campaigns and improve knowledge and awareness about HB among health care workers and higher education students.
Authors: María Elena Cárdenas-Perea; Eduardo Gómez-Conde; Gerardo Santos-López; Irma Pérez-Contreras; María Alicia Díaz-Orea; José Luís Gándara-Ramírez; Othón Rafael Cruz Y López; Luis Márquez-Domínguez; Francisca Sosa-Jurado Journal: Hum Vaccin Immunother Date: 2016-05-12 Impact factor: 3.452
Authors: Paulo R L Machado; Lídia M Machado; Mayume Shibuya; Jamile Rego; Warren D Johnson; Marshall J Glesby Journal: PLoS Negl Trop Dis Date: 2015-08-12
Authors: Livia M Villar; Kycia Maria R do Ó; Leticia P Scalioni; Helena M Cruz; Moyra M Portilho; Ana Carolina F Mendonça; Juliana C Miguel; Andreza S Figueiredo; Adilson J de Almeida; Elisabeth Lampe Journal: Braz J Infect Dis Date: 2015-03-10 Impact factor: 3.257