Literature DB >> 22481422

Neutrophil CD64 as a diagnostic marker in neonatal sepsis.

Iris Streimish1, Matthew Bizzarro, Veronika Northrup, Chao Wang, Sara Renna, Nancy Koval, Fang-Yong Li, Richard Ehrenkranz, Henry M Rinder, Vineet Bhandari.   

Abstract

We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis.

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Year:  2012        PMID： 22481422      PMCID： PMC3375383          DOI： 10.1097/INF.0b013e318256fb07

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  36 in total

1.  Time to positivity of neonatal blood cultures.

Authors:  Y Kumar; M Qunibi; T J Neal; C W Yoxall
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2001-11       Impact factor: 5.747

2.  Early diagnosis of neonatal sepsis using a hematologic scoring system.

Authors:  R L Rodwell; A L Leslie; D I Tudehope
Journal:  J Pediatr       Date:  1988-05       Impact factor: 4.406

3.  Expression of CD64 as a potential marker of neonatal sepsis.

Authors:  Esther Layseca-Espinosa; Luis F Pérez-González; Abraham Torres-Montes; Lourdes Baranda; Hortensia de la Fuente; Yvonne Rosenstein; Roberto González-Amaro
Journal:  Pediatr Allergy Immunol       Date:  2002-10       Impact factor: 6.377

4.  Early markers of late-onset sepsis in premature neonates: clinical, hematological and cytokine profile.

Authors:  Blanca E Gonzalez; Cecilia K Mercado; Linda Johnson; Nancy L Brodsky; Vineet Bhandari
Journal:  J Perinat Med       Date:  2003       Impact factor: 1.901

5.  Rapid detection of microorganisms in blood cultures of newborn infants utilizing an automated blood culture system.

Authors:  J A Garcia-Prats; T R Cooper; V F Schneider; C E Stager; T N Hansen
Journal:  Pediatrics       Date:  2000-03       Impact factor: 7.124

Review 6.  Infections in VLBW infants: studies from the NICHD Neonatal Research Network.

Authors:  Barbara J Stoll; Nellie Hansen
Journal:  Semin Perinatol       Date:  2003-08       Impact factor: 3.300

7.  Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network.

Authors:  Barbara J Stoll; Nellie Hansen; Avroy A Fanaroff; Linda L Wright; Waldemar A Carlo; Richard A Ehrenkranz; James A Lemons; Edward F Donovan; Ann R Stark; Jon E Tyson; William Oh; Charles R Bauer; Sheldon B Korones; Seetha Shankaran; Abbot R Laptook; David K Stevenson; Lu-Ann Papile; W Kenneth Poole
Journal:  Pediatrics       Date:  2002-08       Impact factor: 7.124

8.  Hematologic scoring system in early diagnosis of sepsis in neutropenic newborns.

Authors:  R L Rodwell; K M Taylor; D I Tudehope; P H Gray
Journal:  Pediatr Infect Dis J       Date:  1993-05       Impact factor: 2.129

9.  Neutrophil CD64 is a sensitive diagnostic marker for early-onset neonatal infection.

Authors:  Pak C Ng; Geng Li; Kit M Chui; Winnie C W Chu; Karen Li; Raymond P O Wong; Kai W Chik; Eric Wong; Tai F Fok
Journal:  Pediatr Res       Date:  2004-09-15       Impact factor: 3.756

10.  Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging.

Authors:  M J Bell; J L Ternberg; R D Feigin; J P Keating; R Marshall; L Barton; T Brotherton
Journal:  Ann Surg       Date:  1978-01       Impact factor: 12.969
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  21 in total

Review 1.  Time for a neonatal-specific consensus definition for sepsis.

Authors:  James L Wynn; Hector R Wong; Thomas P Shanley; Matthew J Bizzarro; Lisa Saiman; Richard A Polin
Journal:  Pediatr Crit Care Med       Date:  2014-07       Impact factor: 3.624

2.  Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease.

Authors:  Phillip Minar; Yael Haberman; Ingrid Jurickova; Ting Wen; Marc E Rothenberg; Mi-Ok Kim; Shehzad A Saeed; Robert N Baldassano; Michael Stephens; James Markowitz; Joel Rosh; Wallace V Crandall; Melvin B Heyman; David R Mack; Anne M Griffiths; Susan S Baker; Jeffrey S Hyams; Subra Kugathasan; Lee A Denson
Journal:  Inflamm Bowel Dis       Date:  2014-06       Impact factor: 5.325

3.  Diagnostic value of blood gene expression signatures in active tuberculosis in Thais: a pilot study.

Authors:  N Satproedprai; N Wichukchinda; S Suphankong; W Inunchot; T Kuntima; S Kumpeerasart; S Wattanapokayakit; S Nedsuwan; H Yanai; K Higuchi; N Harada; S Mahasirimongkol
Journal:  Genes Immun       Date:  2015-03-12       Impact factor: 2.676

4.  Neutrophil CD64 as a diagnostic marker of sepsis: impact on neonatal care.

Authors:  Stephanie Lynema; Daniel Marmer; Eric S Hall; Jareen Meinzen-Derr; Paul S Kingma
Journal:  Am J Perinatol       Date:  2014-07-31       Impact factor: 1.862

5.  Flow cytometry in the detection of neonatal sepsis.

Authors:  Volker N Umlauf; Stephan Dreschers; Thorsten W Orlikowsky
Journal:  Int J Pediatr       Date:  2013-02-03

6.  CD64-Neutrophil expression and stress metabolic patterns in early sepsis and severe traumatic brain injury in children.

Authors:  Diana-Michaela Fitrolaki; Helen Dimitriou; Maria Kalmanti; George Briassoulis
Journal:  BMC Pediatr       Date:  2013-03-01       Impact factor: 2.125

7.  Role of Neutrophil CD64 Index as a Screening Marker for Late-Onset Sepsis in Very Low Birth Weight Infants.

Authors:  Florian Kipfmueller; Jessica Schneider; Julia Prusseit; Ioanna Dimitriou; Berndt Zur; Axel R Franz; Peter Bartmann; Andreas Mueller
Journal:  PLoS One       Date:  2015-04-20       Impact factor: 3.240

8.  CD64 as a potential biomarker in septic arthritis.

Authors:  Oddvar Oppegaard; Brita Skodvin; Anne-Kristine Halse; Nina Langeland
Journal:  BMC Infect Dis       Date:  2013-06-19       Impact factor: 3.090

Review 9.  Biomarkers of sepsis.

Authors:  James D Faix
Journal:  Crit Rev Clin Lab Sci       Date:  2013 Jan-Feb       Impact factor: 6.250

Review 10.  Neonatal sepsis: an old problem with new insights.

Authors:  Birju A Shah; James F Padbury
Journal:  Virulence       Date:  2013-11-01       Impact factor: 5.882
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