| Literature DB >> 22481064 |
Pasquale Rescigno1, Elide Matano, Lucia Raimondo, Ciro Mainolfi, Piera Federico, Carlo Buonerba, Rossella Di Trolio, Carmine D'Aniello, Vincenzo Damiano, Giovannella Palmieri, Sabino De Placido, Giuseppe Di Lorenzo.
Abstract
Guidelines on the treatment of metastatic squamous cell carcinoma of the penis are limited to a few prospective trials. Cisplatin-based regimens represent the standard of treatment with promising activity of taxanes. Recently, epidermal growth factor receptor overexpression has been shown in these patients. We treated an elderly man with a docetaxel-cetuximab combination after failure of the cisplatin regimen. We observed a necrosis of the inguinal lymph nodes and a reduction of (18)F-fluorodeoxyglucose uptake at PET/CT scan. Only mild mucositis and skin toxicity had been detected. Our case report, the first in the literature, shows that this combination is active and well tolerated in penile squamous cell carcinoma.Entities:
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Year: 2012 PMID： 22481064 DOI： 10.1097/CAD.0b013e328350ead7
Source DB: PubMed Journal: Anticancer Drugs ISSN： 0959-4973 Impact factor: 2.248