| Literature DB >> 22480852 |
Tetsuya Toba1, Kenji Murata, Junko Futamura, Kyoko Nakanishi, Bitoku Takahashi, Naohiro Takemoto, Minako Tomino, Takashi Nakatsuka, Seiichi Imajo, Megumi Goto, Takashi Yamamura, Sachiko Miyake, Hirokazu Annoura.
Abstract
A series of truncated analogs of α-galactosylceramide with altered ceramide moiety was prepared, and evaluated for Th2-biased response in the context of IL-4/IFN-γ ratio. Phytosphingosine-modified analogs including cyclic, aromatic and ethereal compounds as well as the C-glycoside analog of OCH (2) with their cytokine inducing profile are disclosed.Entities:
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Year: 2012 PMID： 22480852 DOI： 10.1016/j.bmc.2012.03.025
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641