Literature DB >> 22480321

Antioxidant and antiproliferative activity of Hypericum hircinum L. subsp. majus (Aiton) N. Robson essential oil.

Luana Quassinti1, Giulio Lupidi, Filippo Maggi, Gianni Sagratini, Fabrizio Papa, Sauro Vittori, Armandodoriano Bianco, Massimo Bramucci.   

Abstract

This study was undertaken to assess the antioxidant and antiproliferative potential of the essential oil of Hypericum hircinum L. subsp. majus (Aiton) N. Robson. Analysis of the oil composition revealed that sesquiterpene hydrocarbons (69.3%) dominate, cis-β-guaiene, δ-selinene and (E)-caryophyllene being the most representative. Significant values of antioxidant activity were found using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging assays. The essential oil revealed antiproliferative activity as evaluated on human glioblastoma (T98G), human prostatic adenocarcinoma (PC3), human squamous carcinoma (A431) and mouse melanoma (B16-F1) tumour cell lines by MTT assay.

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Year:  2012        PMID： 22480321     DOI： 10.1080/14786419.2012.677044

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  7 in total

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Authors:  Giovanni Caprioli; Alessia Alunno; Daniela Beghelli; Armandodoriano Bianco; Massimo Bramucci; Claudio Frezza; Romilde Iannarelli; Fabrizio Papa; Luana Quassinti; Gianni Sagratini; Bruno Tirillini; Alessandro Venditti; Sauro Vittori; Filippo Maggi
Journal:  Front Plant Sci       Date:  2016-03-01       Impact factor: 5.753

7.  Chemical Characteristics and Anticancer Activity of Essential Oil from Arnica Montana L. Rhizomes and Roots.

Authors:  Piotr Sugier; Joanna Jakubowicz-Gil; Danuta Sugier; Radosław Kowalski; Urszula Gawlik-Dziki; Barbara Kołodziej; Dariusz Dziki
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  7 in total

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