Literature DB >> 22479297

A case of needle fixation.

Yvonne Treffurth1, Hem Raj Pal.   

Abstract

Needle fixation is frequently missed and dismissed by clinicians and patients. However, ignoring this condition can have severe consequences, such as septicaemia, thrombosis, blood borne viruses, and is associated with an overall poor prognosis of drug dependence.Here we describe a 37-year-old man who presented with 20-year history of polydrug dependence, drug-induced psychosis and antisocial personality disorder. He was found to also have a 5-year history of intermittent needle fixation. His injecting behaviour and drug use improved significantly with fluoxetine while being on methadone maintenance.At present there is little evidence for any effective treatment strategies for needle fixation. The current recommended treatment consists of cognitive behavioural therapy and cue exposure. Whether fluoxetine constitutes an effective management strategy remains to be seen.

Entities:  

Year:  2010        PMID: 22479297      PMCID: PMC3047519          DOI: 10.1136/bcr.11.2009.2458

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  Needle fixation, the drug user's perspective: a qualitative study.

Authors:  A J McBride; R M Pates; K Arnold; N Ball
Journal:  Addiction       Date:  2001-07       Impact factor: 6.526

2.  Interactions of fluoxetine with metabolism of dopamine and serotonin in rat brain regions.

Authors:  R J Baldessarini; E R Marsh; N S Kula
Journal:  Brain Res       Date:  1992-05-01       Impact factor: 3.252

3.  The mechanism of placebo analgesia.

Authors:  J D Levine; N C Gordon; H L Fields
Journal:  Lancet       Date:  1978-09-23       Impact factor: 79.321

4.  Fluoxetine suppresses morphine tolerance and dependence: modulation of NO-cGMP/DA/serotoninergic pathways.

Authors:  V P Singh; N K Jain; S K Kulkarni
Journal:  Methods Find Exp Clin Pharmacol       Date:  2003-05
  4 in total
  1 in total

Review 1.  Neurobiology of reward-related learning.

Authors:  Ewa Galaj; Robert Ranaldi
Journal:  Neurosci Biobehav Rev       Date:  2021-02-10       Impact factor: 8.989

  1 in total

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