Literature DB >> 22477740

Benign metastasising leiomyoma after hysterectomy and bilateral salpingo-oophorectomy.

Manisha M Beck1, Bivas Biswas, Aparajita D'Souza, Ramani Kumar.   

Abstract

Benign metastasising leiomyomatosis is a rare condition affecting women in the reproductive age-group with a history of uterine fibroids, who have undergone treatment by myomectomy or hysterectomy. It is characterised by development of multiple, indolent, smooth muscle tumours outside the uterus, most commonly in the lungs, and manifests several years after the uterine surgery. We describe the case of a young woman, who had undergone total abdominal hysterectomy and bilateral salpingo-oophorectomy for multiple fibroids and a right ovarian cyst. After 5 years of being on oestrogen replacement therapy, she was detected to have benign metastasising leiomyoma, for which an additional laparotomy was performed. At laparotomy, removal of the pelvic mass was associated with several complications. The metastatic lesions in the lung responded well to progestogens (megestrol acetate) alone as evidenced by regression of the lesions detected at follow-up after 6 months and 1 year.

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Year:  2012        PMID: 22477740

Source DB:  PubMed          Journal:  Hong Kong Med J        ISSN: 1024-2708            Impact factor:   2.227


  8 in total

1.  Concurrent Benign Metastasizing Leiomyoma in the Abdominal Wall and Pelvic Cavity: A Case Report and Review of the Literature.

Authors:  Yue Li; Tongtong Xu; Mingdan Wang; Lili Jiang; Qifang Liu; Kuiran Liu
Journal:  Front Surg       Date:  2022-04-18

Review 2.  Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review.

Authors:  Erin I Lewis; Rebecca J Chason; Alan H DeCherney; Alicia Armstrong; John Elkas; Aradhana M Venkatesan
Journal:  Fertil Steril       Date:  2013-03-05       Impact factor: 7.329

3.  Unusual Case of a Torted Mesenteric Fibroid.

Authors:  Rawan Bajis; Gregg Eloundou
Journal:  Case Rep Obstet Gynecol       Date:  2018-06-07

4.  Benign metastasizing leiomyoma of the lung.

Authors:  Eun Young Ki; Seon Jeong Hwang; Keun Ho Lee; Jong Sup Park; Soo Young Hur
Journal:  World J Surg Oncol       Date:  2013-10-17       Impact factor: 2.754

5.  Multimodality Evaluation of Intravenous Leiomyomatosis: A Rare, Benign but Potentially Life-Threatening Tumor.

Authors:  Reinaldo J Fornaris; Melisa Rivera; Luis Jiménez; José Maldonado
Journal:  Am J Case Rep       Date:  2015-11-07

6.  Whole exome sequencing of benign pulmonary metastasizing leiomyoma reveals mutation in the BMP8B gene.

Authors:  Deniss Sõritsa; Hindrek Teder; Retlav Roosipuu; Hannes Tamm; Triin Laisk-Podar; Pille Soplepmann; Alan Altraja; Andres Salumets; Maire Peters
Journal:  BMC Med Genet       Date:  2018-01-31       Impact factor: 2.103

7.  Recurrent benign leiomyomas after total abdominal hysterectomy. Rich or poor estrogenic environment may lead to their recurrence?

Authors:  Konstantinos Kyriakopoulos; Ekaterini Domali; Sofoklis Stavrou; Alexandros Rodolakis; Dimitrios Loutradis; Peter Drakakis
Journal:  Int J Surg Case Rep       Date:  2018-02-22

8.  Intravenous leiomyomatosis is inclined to a solid entity different from uterine leiomyoma based on RNA-seq analysis with RT-qPCR validation.

Authors:  Wenze Wang; Yanfeng Wang; Fei Chen; Ming Zhang; Rujing Jia; Xingrong Liu; Chaoji Zhang; Jiang Shao; Ninghai Cheng; Guotao Ma; Zhaohui Zhu; Qi Miao; Zhiyong Liang
Journal:  Cancer Med       Date:  2020-05-05       Impact factor: 4.452

  8 in total

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