Literature DB >> 22477595

Prolongation of QRS duration and axis deviation in the right bundle branch block are not markers for left ventricular systolic dysfunction.

Eric R Uyguanco1, Anthony Mirandi, Ghazanfar Qureshi, Jason Lazar, Amit Chhabra, John Kassotis.   

Abstract

BACKGROUND: Right bundle branch block (RBBB) is not commonly associated with structural heart disease and left ventricular (LV) systolic dysfunction. The purpose of the present study was to determine whether the QRS duration and degree of right axis deviation (RAD) or left axis deviation (LAD) in patients with RBBB predicted a subset of patients with significant LV systolic dysfunction.
METHODS: In the present prospective study, 75 of 200 consecutive patients with RBBB had their ejection fraction (EF) evaluated by echocardiography. The relationship among QRS duration, axis and EF was derived.
RESULTS: There were no significant differences in sex and EF among the patients with a normal axis, RAD or LAD. The EFs of patients with a normal axis (n=27), RAD (n=15) and LAD (n=33) were 52±15%, 49±14% and 46±17%, respectively (P=0.35). The mean EF (46±16%) of patients with a QRS duration of 150 ms or greater (n=53) was not significantly different from the mean EF (49±18%) of patients with a QRS duration of less than 150 ms (n=22) (P=0.54). For patients with a QRS of 120 ms or greater and less than 150 ms (n=22), QRS of 150 ms or greater and 180 ms or less (n=48), and QRS of greater than 180 ms (n=5), the mean EFs were 49±18%, 47±16% and 44±7%, respectively (P=0.78). There was no significant correlation between QRS duration and EF in all patients (r=0.03, P=0.83), EF and RAD (r=0.38, P=0.16) or EF and LAD (r=0.26, P=0.14).
CONCLUSIONS: In patients with RBBB, the QRS duration and axis do not have a significant relationship with EF. Furthermore, prolongation of the QRS duration (150 ms or greater) in the presence of RBBB is not a marker of significant LV systolic dysfunction.

Entities:  

Year:  2010        PMID: 22477595      PMCID: PMC3005414          DOI: 10.1055/s-0031-1278372

Source DB:  PubMed          Journal:  Int J Angiol        ISSN: 1061-1711


  22 in total

1.  Usefulness of biventricular pacing in patients with congestive heart failure and right bundle branch block.

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6.  Prolonged QRS duration (QRS >/=170 ms) and left axis deviation in the presence of left bundle branch block: A marker of poor left ventricular systolic function?

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Journal:  Am Heart J       Date:  2001-11       Impact factor: 4.749

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Authors:  Anne M Dubin; Jeffrey A Feinstein; V Mohan Reddy; Frank L Hanley; George F Van Hare; David N Rosenthal
Journal:  Circulation       Date:  2003-05-05       Impact factor: 29.690

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10.  The epidemiology of right bundle branch block and its association with cardiovascular morbidity--the Reykjavik Study.

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Journal:  Eur Heart J       Date:  1993-12       Impact factor: 29.983

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  1 in total

1.  Right ventricular failure predicted from right bundle branch block: cardiac magnetic resonance imaging validation.

Authors:  Santhosh R Devarapally; Sameer Arora; Ali Ahmad; Mike Sood; Amaar El Sergany; Terrence Sacchi; Barry Saul; Rahul Gaglani; John Heitner
Journal:  Cardiovasc Diagn Ther       Date:  2016-10
  1 in total

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