Literature DB >> 22477326

Management of small asymptomatic abdominal aortic aneurysms - a review.

H Silaghi1, A Branchereau, S Malikov, Aurel Andercou.   

Abstract

The approach for abdominal aortic aneurysms (AAAs) larger than 55 mm is well defined due to the risk of rupture being higher than 10% per year, and a 30-day perioperative mortality rate between 2.5% and 5%. However, the approach for small asymptomatic AAAs is less well defined.There are different definitions given to describe a small AAA. The one the authors accepted and applied is "a localized, permanent and irreversible dilation of the aorta of at least 50% in relation to the normal adjacent infrarenal or suprarenal aorta, with a maximum diameter between 30-55 mm".The investigators of the largest study on small AAAs (United Kingdom Small Aneurysm Trial [UK-SAT]) concluded, in brief, that ultrasound monitoring is the most appropriate solution because the results do not support a policy of surgical restoration for AAAs with a diameter of between 40 mm and 55 mm.The aim of the present review article is to highlight several challenges that could change the limits or create a more flexible deciding factor in the management of AAAs. There are multiple factors that influence surgical decision-making, and the limit on aneurysm diameter that indicates surgery should depend on the patient's age, life expectancy, general status, associated diseases, diameter in relation to body mass, risk factors, sex, anxiety and compliance during the follow-up period. Monitoring is an acceptable alternative for AAAs between 40 mm and 55 mm, and is probably the best solution for high-risk patients. Surgery is the most reasonable solution for patients who are at moderate risk, have a significant life expectancy, are less than 70 to 75 years of age, and/or have aortic aneurysms larger than 50 mm.

Entities:  

Year:  2007        PMID: 22477326      PMCID: PMC2733031          DOI: 10.1055/s-0031-1278264

Source DB:  PubMed          Journal:  Int J Angiol        ISSN: 1061-1711


  49 in total

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  3 in total

Review 1.  The Role of Imaging in Health Screening: Screening for Specific Conditions.

Authors:  David H Ballard; Kirsteen R Burton; Nikita Lakomkin; Shannon Kim; Prabhakar Rajiah; Midhir J Patel; Parisa Mazaheri; Gary J Whitman
Journal:  Acad Radiol       Date:  2020-05-11       Impact factor: 3.173

2.  Noninvasive imaging of vascular permeability to predict the risk of rupture in abdominal aortic aneurysms using an albumin-binding probe.

Authors:  Lisa C Adams; Julia Brangsch; Carolin Reimann; Jan O Kaufmann; Kristin Nowak; Rebecca Buchholz; Uwe Karst; Rene M Botnar; Bernd Hamm; Marcus R Makowski
Journal:  Sci Rep       Date:  2020-02-24       Impact factor: 4.379

3.  Profiling of Histone Modifications Reveals Epigenomic Dynamics During Abdominal Aortic Aneurysm Formation in Mouse Models.

Authors:  Jacob Greenway; Nicole Gilreath; Sagar Patel; Tetsuo Horimatsu; Mary Moses; David Kim; Lauren Reid; Mourad Ogbi; Yang Shi; Xin-Yun Lu; Mrinal Shukla; Richard Lee; Yuqing Huo; Lufei Young; Ha Won Kim; Neal L Weintraub
Journal:  Front Cardiovasc Med       Date:  2020-10-30
  3 in total

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