Frank I Scott1, Ryan A McConnell, Matthew E Lewis, James D Lewis. 1. Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA. frankis@mail.med.upenn.edu
Abstract
OBJECTIVES: Significant advances have been made in clinical and epidemiologic research methods over the past 30 years. We sought to demonstrate the impact of these advances on published gastroenterology research from 1980 to 2010. METHODS: Twenty original clinical articles were randomly selected from each of three journals from 1980, 1990, 2000, and 2010. Each article was assessed for topic, whether the outcome was clinical or physiologic, study design, sample size, number of authors and centers collaborating, reporting of various statistical methods, and external funding. RESULTS: From 1980 to 2010, there was a significant increase in analytic studies, clinical outcomes, number of authors per article, multicenter collaboration, sample size, and external funding. There was increased reporting of P values, confidence intervals, and power calculations, and increased use of large multicenter databases, multivariate analyses, and bioinformatics. CONCLUSIONS: The complexity of clinical gastroenterology and hepatology research has increased dramatically, highlighting the need for advanced training of clinical investigators.
OBJECTIVES: Significant advances have been made in clinical and epidemiologic research methods over the past 30 years. We sought to demonstrate the impact of these advances on published gastroenterology research from 1980 to 2010. METHODS: Twenty original clinical articles were randomly selected from each of three journals from 1980, 1990, 2000, and 2010. Each article was assessed for topic, whether the outcome was clinical or physiologic, study design, sample size, number of authors and centers collaborating, reporting of various statistical methods, and external funding. RESULTS: From 1980 to 2010, there was a significant increase in analytic studies, clinical outcomes, number of authors per article, multicenter collaboration, sample size, and external funding. There was increased reporting of P values, confidence intervals, and power calculations, and increased use of large multicenter databases, multivariate analyses, and bioinformatics. CONCLUSIONS: The complexity of clinical gastroenterology and hepatology research has increased dramatically, highlighting the need for advanced training of clinical investigators.
Authors: Timothy C Wang; Fabio Cominelli; David E Fleischer; James M Gordon; Robert M Glickman; David Limsui; Kenneth R McQuaid; Marshall Montrose; Pankaj J Pasricha; Don W Powell; William A Rowe; William J Sandborn; Andrea Todisco Journal: Gastroenterology Date: 2008-11 Impact factor: 22.682
Authors: Russell Harris; Linda S Kinsinger; Sue Tolleson-Rinehart; Anthony J Viera; Georgette Dent Journal: Acad Med Date: 2008-04 Impact factor: 6.893
Authors: Briget da Graca; Benjamin D Pollock; Teresa K Phan; Chris Carlisi; Tavia I Gonzalez Peña; Giovanni Filardo Journal: Mayo Clin Proc Innov Qual Outcomes Date: 2019-01-18