Earlier detection of bone metastases from pleomorphic liposarcoma in a pediatric patient by FDG PET/CT than planar 99mTc MDP bone scan.

Bone scintigraphy using (99m)TC MDP (technetium-99m methylene diphosphonate) is a routine procedure for evaluation of osteoblastic metastases; however, its sensitivity compared with FDG PET/CT in a variety of malignancies remains to be established. We report a case of multiple osseous metastases revealed by FDG PET/CT in an 8-year-old girl with pleomorphic liposarcoma. Many of these osseous lesions were not visualized on the MDP planar bone scintigraphy performed 24 hours after PET/CT scan, becoming evident only on repeat bone scan performed 3 months later. The case suggests that FDG PET/CT has higher sensitivity in detecting osteoblastic metastases in pleomorphic liposarcoma.