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Literature DB >> 22475792

Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds.

Nadezda Fomina¹, Cathryn L McFearin, Adah Almutairi.

Abstract

Photoactivation using two photons of NIR allows non-invasive biological manipulation. We applied the principle of dendritic amplification to improve the materials' sensitivity to NIR light. Light induced uncaging or release of L-glutamic acid was 2.8 fold higher when incorporating 4-bromo-7-hydroxycoumarin (Bhc) with self-immolative dendrimers compared with Bhc directly conjugated to L-glutamic acid.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2012 PMID： 22475792 PMCID： PMC3421069 DOI： 10.1039/c2cc00072e

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

18 in total

1. "Cascade-release dendrimers" liberate all end groups upon a single triggering event in the dendritic core.

Authors: Franciscus M H de Groot; Carsten Albrecht; Ralph Koekkoek; Patrick H Beusker; Hans W Scheeren
Journal: Angew Chem Int Ed Engl Date: 2003-09-29 Impact factor: 15.336

2. Self-immolative dendrimers.

Authors: Roey J Amir; Neta Pessah; Marina Shamis; Doron Shabat
Journal: Angew Chem Int Ed Engl Date: 2003-09-29 Impact factor: 15.336

3. Dendritic chain reaction: responsive release of hydrogen peroxide upon generation and enzymatic oxidation of methanol.

Authors: Michal Avital-Shmilovici; Doron Shabat
Journal: Bioorg Med Chem Date: 2010-02-25 Impact factor: 3.641

4. Receiver-amplifier, self-immolative dendritic device.

Authors: Roey J Amir; Eyal Danieli; Doron Shabat
Journal: Chemistry Date: 2007 Impact factor: 5.236

5. Remarkable drug-release enhancement with an elimination-based AB3 self-immolative dendritic amplifier.

Authors: Amit Sagi; Ehud Segal; Ronit Satchi-Fainaro; Doron Shabat
Journal: Bioorg Med Chem Date: 2007-03-21 Impact factor: 3.641

6. Chemical two-photon uncaging: a novel approach to mapping glutamate receptors.

Authors: D L Pettit; S S Wang; K R Gee; G J Augustine
Journal: Neuron Date: 1997-09 Impact factor: 17.173

7. UV and near-IR triggered release from polymeric nanoparticles.

Authors: Nadezda Fomina; Cathryn McFearin; Marleen Sermsakdi; Osayimwense Edigin; Adah Almutairi
Journal: J Am Chem Soc Date: 2010-07-21 Impact factor: 15.419

8. Water-soluble, donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: highly efficient two-photon uncaging of the neurotransmitter γ-aminobutyric acid at λ = 800 nm.

Authors: Loïc Donato; Alexandre Mourot; Christopher M Davenport; Cyril Herbivo; David Warther; Jérémie Léonard; Frédéric Bolze; Jean-François Nicoud; Richard H Kramer; Maurice Goeldner; Alexandre Specht
Journal: Angew Chem Int Ed Engl Date: 2012-01-11 Impact factor: 15.336

Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds.

1. "Cascade-release dendrimers" liberate all end groups upon a single triggering event in the dendritic core.

2. Self-immolative dendrimers.

3. Dendritic chain reaction: responsive release of hydrogen peroxide upon generation and enzymatic oxidation of methanol.

4. Receiver-amplifier, self-immolative dendritic device.

5. Remarkable drug-release enhancement with an elimination-based AB3 self-immolative dendritic amplifier.

6. Chemical two-photon uncaging: a novel approach to mapping glutamate receptors.

7. UV and near-IR triggered release from polymeric nanoparticles.

8. Water-soluble, donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: highly efficient two-photon uncaging of the neurotransmitter γ-aminobutyric acid at λ = 800 nm.

9. Low power, biologically benign NIR light triggers polymer disassembly.

10. Two-color, two-photon uncaging of glutamate and GABA.

1. Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Review 2. Stimulus-Responsive Nanomedicines for Disease Diagnosis and Treatment.

3. Photodegradable polyesters for triggered release.