BACKGROUND: Although chronic obstructive pulmonary disease (COPD) is mostly related to tobacco smoking, a variable proportion of COPD occurs in never smokers. We investigated differences between COPD in never smokers compared with smokers and subjects without COPD. METHODS: PLATINO is a cross-sectional population-based study of five Latin American cities. COPD was defined as postbronchodilator FEV(1)/FVC <0.70 and FEV(1) <80% of predicted values. RESULTS: Among 5,315 subjects studied, 2278 were never smokers and 3036 were ever smokers. COPD was observed in 3.5% of never smokers and in 7.5% of ever smokers. Never smokers with COPD were most likely older and reported a medical diagnosis of asthma or previous tuberculosis. Underdiagnosis was as common in obstructed patients who never smoked as in ever smokers. CONCLUSIONS: Never smokers comprised 26% of all individuals with airflow obstruction. Obstruction was associated with female gender, older age and a diagnosis of asthma or tuberculosis.
BACKGROUND: Although chronic obstructive pulmonary disease (COPD) is mostly related to tobacco smoking, a variable proportion of COPD occurs in never smokers. We investigated differences between COPD in never smokers compared with smokers and subjects without COPD. METHODS: PLATINO is a cross-sectional population-based study of five Latin American cities. COPD was defined as postbronchodilator FEV(1)/FVC <0.70 and FEV(1) <80% of predicted values. RESULTS: Among 5,315 subjects studied, 2278 were never smokers and 3036 were ever smokers. COPD was observed in 3.5% of never smokers and in 7.5% of ever smokers. Never smokers with COPD were most likely older and reported a medical diagnosis of asthma or previous tuberculosis. Underdiagnosis was as common in obstructed patients who never smoked as in ever smokers. CONCLUSIONS: Never smokers comprised 26% of all individuals with airflow obstruction. Obstruction was associated with female gender, older age and a diagnosis of asthma or tuberculosis.
Authors: Su Hwan Lee; Eu Dong Hwang; Ju Eun Lim; Sungwoo Moon; Young Ae Kang; Ji Ye Jung; Moo Suk Park; Se Kyu Kim; Joon Chang; Young Sam Kim; Song Yee Kim Journal: Lung Date: 2016-04-01 Impact factor: 2.584
Authors: Kevin Mortimer; Stephen B Gordon; Surinder K Jindal; Roberto A Accinelli; John Balmes; William J Martin Journal: Chest Date: 2012-11 Impact factor: 9.410
Authors: Andreas Horner; Joan B Soriano; Milo A Puhan; Michael Studnicka; Bernhard Kaiser; Lowie E G W Vanfleteren; Louisa Gnatiuc; Peter Burney; Marc Miravitlles; Francisco García-Rio; Julio Ancochea; Ana M Menezes; Rogelio Perez-Padilla; Maria Montes de Oca; Carlos A Torres-Duque; Andres Caballero; Mauricio González-García; Sonia Buist; Maria Flamm; Bernd Lamprecht Journal: Respir Res Date: 2017-08-23
Authors: Rogelio Pérez-Padilla; Rosario Fernandez-Plata; Maria Montes de Oca; Maria Victorina Lopez-Varela; Jose R Jardim; Adriana Muiño; Gonzalo Valdivia; Ana Maria B Menezes Journal: PLoS One Date: 2017-05-04 Impact factor: 3.240