Literature DB >> 22475093

IL-36 a new member of the IL-1 family cytokines.

D Tripodi, F Conti, M Rosati, G Maccauro, A Saggini, E Cianchetti, D Angelucci, M Fulcheri, S Tetè, V Salini, A Caraffa, P Antinolfi, E Toniato, M L Castellani, P Conti, T C Theoharides.   

Abstract

Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.

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Year:  2012        PMID： 22475093

Source DB:  PubMed          Journal:  J Biol Regul Homeost Agents        ISSN： 0393-974X            Impact factor:   1.711


  7 in total

1.  IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.

Authors:  S E Russell; R M Horan; A M Stefanska; A Carey; G Leon; M Aguilera; D Statovci; T Moran; P G Fallon; F Shanahan; E K Brint; S Melgar; S Hussey; P T Walsh
Journal:  Mucosal Immunol       Date:  2016-01-27       Impact factor: 7.313

2.  Opposing Effects of IL-1Ra and IL-36Ra on Innate Immune Response to Pseudomonas aeruginosa Infection in C57BL/6 Mouse Corneas.

Authors:  Nan Gao; Rao Me; Chenyang Dai; Berhane Seyoum; Fu-Shin X Yu
Journal:  J Immunol       Date:  2018-06-11       Impact factor: 5.422

Review 3.  IL-6 as a druggable target in psoriasis: focus on pustular variants.

Authors:  Andrea Saggini; Sergio Chimenti; Andrea Chiricozzi
Journal:  J Immunol Res       Date:  2014-07-13       Impact factor: 4.818

4.  NSC828779 Alleviates Renal Tubulointerstitial Lesions Involving Interleukin-36 Signaling in Mice.

Authors:  Shin-Ruen Yang; Szu-Chun Hung; Lichieh Julie Chu; Kuo-Feng Hua; Chyou-Wei Wei; I-Lin Tsai; Chih-Chin Kao; Chih-Chien Sung; Pauling Chu; Chung-Yao Wu; Ann Chen; Alexander T H Wu; Feng-Cheng Liu; Hsu-Shan Huang; Shuk-Man Ka
Journal:  Cells       Date:  2021-11-06       Impact factor: 6.600

5.  Interleukin(IL)-36α and IL-36γ Induce Proinflammatory Mediators from Human Colonic Subepithelial Myofibroblasts.

Authors:  Toshihiro Kanda; Atsushi Nishida; Kenichiro Takahashi; Kentaro Hidaka; Hirotsugu Imaeda; Osamu Inatomi; Shigeki Bamba; Mitsushige Sugimoto; Akira Andoh
Journal:  Front Med (Lausanne)       Date:  2015-09-22

Review 6.  Therapeutic use of dendritic cells to promote the extranodal priming of anti-tumor immunity.

Authors:  Lu Chen; Kellsye L Fabian; Jennifer L Taylor; Walter J Storkus
Journal:  Front Immunol       Date:  2013-11-29       Impact factor: 7.561

7.  Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts.

Authors:  Kenichiro Takahashi; Atsushi Nishida; Makoto Shioya; Hirotsugu Imaeda; Shigeki Bamba; Osamu Inatomi; Tomoharu Shimizu; Katsuyuki Kitoh; Akira Andoh
Journal:  PLoS One       Date:  2015-11-12       Impact factor: 3.240
  7 in total

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