Literature DB >> 22474940

A novel anticancer diterpenoid from Jatropha gossypifolia.

Abiodun Falodun1, Udo Kragl, Serge-Mitherand Tengho Touem, Alexander Villinger, Thomas Fahrenwaldt, Peter Langer.   

Abstract

Jatropha gossypifolia root bark is used in ethnomedicine for bacterial infections and cancer of the lungs. Phytochemical investigation resulted in the isolation and characterization of a potent anticancer and novel lathyrane diterpenoid compound, abiodone, with an unusual methylene group. The structure of this novel compound was established by 1D, and 2D NMR spectroscopic experiments a nd confirmed by X-ray analysis.

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Year:  2012        PMID: 22474940

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  2 in total

1.  Isolation of antileishmanial, antimalarial and antimicrobial metabolites from Jatropha multifida.

Authors:  Abiodun Falodun; Vincent Imieje; Osayewenre Erharuyi; Ahomafor Joy; Peter Langer; Melissa Jacob; Shabanna Khan; Mohammed Abaldry; Mark Hamann
Journal:  Asian Pac J Trop Biomed       Date:  2014-05

Review 2.  Jatropha gossypiifolia L. (Euphorbiaceae): A Review of Traditional Uses, Phytochemistry, Pharmacology, and Toxicology of This Medicinal Plant.

Authors:  Juliana Félix-Silva; Raquel Brandt Giordani; Arnóbio Antonio da Silva; Silvana Maria Zucolotto; Matheus de Freitas Fernandes-Pedrosa
Journal:  Evid Based Complement Alternat Med       Date:  2014-06-05       Impact factor: 2.629

  2 in total

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