BACKGROUND: Mucosal melanoma of the head and neck is rare and is associated with a poor prognoses because of locoregional failure and distant metastasis. The aim of our study was to review the characteristics of these patients in northern Japan and to analyze their outcomes. METHODS: The medical records of 94 patients who had been provided initial treatment in 12 institutes from 1998 to 2007 were reviewed. RESULTS: When the 5-year overall survival rates of patients were evaluated, we found that the survival rates of patients treated by chemotherapy were significantly lower than those of patients treated by surgery or radiation. The survival rates of the single-treatment modality, 2-modality, and ≥3-modality groups were 23.4%, 38.0%, and 33.6%, respectively. CONCLUSION: Our results suggest that patients who underwent combined treatment had better prognoses. However, we found that chemotherapy had no additional survival benefits.
BACKGROUND:Mucosal melanoma of the head and neck is rare and is associated with a poor prognoses because of locoregional failure and distant metastasis. The aim of our study was to review the characteristics of these patients in northern Japan and to analyze their outcomes. METHODS: The medical records of 94 patients who had been provided initial treatment in 12 institutes from 1998 to 2007 were reviewed. RESULTS: When the 5-year overall survival rates of patients were evaluated, we found that the survival rates of patients treated by chemotherapy were significantly lower than those of patients treated by surgery or radiation. The survival rates of the single-treatment modality, 2-modality, and ≥3-modality groups were 23.4%, 38.0%, and 33.6%, respectively. CONCLUSION: Our results suggest that patients who underwent combined treatment had better prognoses. However, we found that chemotherapy had no additional survival benefits.
Authors: Luiz Fernando Barbosa de Paulo; João Paulo Silva Servato; Roberta Rezende Rosa; Maiolino Thomaz Fonseca Oliveira; Paulo Rogério de Faria; Sindeval José da Silva; Sergio Vitorino Cardoso; Adriano Mota Loyola Journal: Oral Maxillofac Surg Date: 2015-05-03
Authors: Moran Amit; Samantha Tam; Ahmed S Abdelmeguid; Michael E Kupferman; Shirley Y Su; Shaan M Raza; Franco DeMonte; Ehab Y Hanna Journal: J Neurol Surg B Skull Base Date: 2017-07-31
Authors: K Luna-Ortiz; M Aguilar-Romero; V Villavicencio-Valencia; E Zepeda-Castilla; H Vidrio-Morgado; N Peteuil; A Mosqueda-Taylor Journal: Med Oral Patol Oral Cir Bucal Date: 2016-07-01