BACKGROUND: Few comprehensive epidemiological studies of the prevalence of Parkinson's disease (PD) have been undertaken in Arab countries, and none has been carried out in Egypt. A community-based survey was conducted in the Assiut Governorate to estimate the prevalence and clinical profile of PD. METHODS: A community-based study was carried out, with random sampling of 7 districts, involving 6,498 inhabitants. Out of this sample, 578 subjects dropped out, leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 urban residents (61.8%) and 2,260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire, the Unified Parkinson Disease Rating Scale and the Non-Motor Symptoms Scale for PD. RESULTS: Thirty-nine subjects were found to have parkinsonism, giving a crude prevalence rate of 659/100,000 inhabitants. Of these subjects, 33 were diagnosed with PD (21 males), with a mean age of 66.9 ± 8.4 years, a crude prevalence rate of 557/100,000 and an age-specific prevalence rate (≥50 years old) of 2,748/100,000. There were more males than females (3,395 vs. 1,989/100,000), but the difference was not significant. The highest age-specific prevalence rate was recorded among subjects 70-79 years old (7,263/100,000). There was a significantly higher prevalence among rural than urban inhabitants (973 vs. 301/100,000) and among illiterate than literate persons (1,103 vs. 280/100,000). The clinical profile of our patients was similar to that of other populations but was characterized by a high prevalence of mood/cognition dysfunction and gastrointestinal symptoms; there were few reported perceptual problems. CONCLUSION: The overall prevalence of PD was high, especially in older adults.
BACKGROUND: Few comprehensive epidemiological studies of the prevalence of Parkinson's disease (PD) have been undertaken in Arab countries, and none has been carried out in Egypt. A community-based survey was conducted in the Assiut Governorate to estimate the prevalence and clinical profile of PD. METHODS: A community-based study was carried out, with random sampling of 7 districts, involving 6,498 inhabitants. Out of this sample, 578 subjects dropped out, leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 urban residents (61.8%) and 2,260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire, the Unified Parkinson Disease Rating Scale and the Non-Motor Symptoms Scale for PD. RESULTS: Thirty-nine subjects were found to have parkinsonism, giving a crude prevalence rate of 659/100,000 inhabitants. Of these subjects, 33 were diagnosed with PD (21 males), with a mean age of 66.9 ± 8.4 years, a crude prevalence rate of 557/100,000 and an age-specific prevalence rate (≥50 years old) of 2,748/100,000. There were more males than females (3,395 vs. 1,989/100,000), but the difference was not significant. The highest age-specific prevalence rate was recorded among subjects 70-79 years old (7,263/100,000). There was a significantly higher prevalence among rural than urban inhabitants (973 vs. 301/100,000) and among illiterate than literate persons (1,103 vs. 280/100,000). The clinical profile of our patients was similar to that of other populations but was characterized by a high prevalence of mood/cognition dysfunction and gastrointestinal symptoms; there were few reported perceptual problems. CONCLUSION: The overall prevalence of PD was high, especially in older adults.
Authors: Thomas W Rösler; Mohamed Salama; Ali S Shalash; Eman M Khedr; Abdelhalim El-Tantawy; Gharib Fawi; Amal El-Motayam; Ehab El-Seidy; Mohamed El-Sherif; Mohamed El-Gamal; Mohamed Moharram; Mohammad El-Kattan; Muhammad Abdel-Naby; Samia Ashour; Ulrich Müller; Astrid Dempfle; Gregor Kuhlenbäumer; Günter U Höglinger Journal: Sci Rep Date: 2018-11-08 Impact factor: 4.379
Authors: Daniel J van Wamelen; Anna Sauerbier; Valentina Leta; Carmen Rodriguez-Blazquez; Cristian Falup-Pecurariu; Mayela Rodriguez-Violante; Alexandra Rizos; Y Tsuboi; Vinod Metta; Roongroj Bhidayasiri; Kalyan Bhattacharya; Rupam Borgohain; L K Prashanth; Raymond Rosales; Simon Lewis; Victor Fung; Madhuri Behari; Vinay Goyal; Asha Kishore; Santiago Perez Lloret; Pablo Martinez-Martin; K Ray Chaudhuri Journal: Sci Rep Date: 2021-05-05 Impact factor: 4.379
Authors: Hanan Khalil; Lana M Chahine; Junaid Siddiqui; Mehri Salari; Shaimaa El-Jaafary; Zakiyah Aldaajani; Mishal Abu Al-Melh; Tareq Mohammad Mohammad; Muneer Abu Snineh; Nadir A Syed; Mohit Bhatt; Mohammad Ahsan Habib; Majed Habahbeh; Samer D Tabbal; Beomseok Jeon; Jawad A Bajwa Journal: J Parkinsons Dis Date: 2020 Impact factor: 5.568