OBJECTIVE: Percutaneous coronary interventions (PCIs) are increasingly being performed worldwide to treat patients with coronary artery disease. However, studies on the influence of ethnicity on clinical outcomes after PCI are scarce. In our current analysis, we evaluate the differences in baseline clinical, angiographic and procedural characteristics, and 12-month clinical outcomes in patients undergoing nonurgent PCI in Western Europe and in Asia. METHODS: We analyzed all patients enrolled in the worldwide e-HEALING (electronic Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth) registry living in Western Europe and Asia. All patients were treated with at least one endothelial progenitor cell capturing stent. The main study outcome was target vessel failure at the 12-month follow-up, defined as the composite of cardiac death or myocardial infarction and target vessel revascularization. RESULTS: A total of 3504 patients, 2873 living in Western Europe and 731 living in Asia, were assessed in the current analysis. Almost all of the baseline clinical and angiographic characteristics differed significantly between both populations. Target vessel failure at the 12-month follow-up occurred in 11.4% of the Western Europe patients and in 5.6% of the Asian patients (P<0.01). CONCLUSION: We conclude that differences exist in the baseline, angiographic, and procedural characteristics between Western European and Asian patients undergoing nonurgent PCI. In addition, the 1-year clinical outcomes differ significantly after PCI between Western European and Asian patients. Our results indicate that reports from studies performed worldwide should include both overall and regional subgroup outcomes.
OBJECTIVE: Percutaneous coronary interventions (PCIs) are increasingly being performed worldwide to treat patients with coronary artery disease. However, studies on the influence of ethnicity on clinical outcomes after PCI are scarce. In our current analysis, we evaluate the differences in baseline clinical, angiographic and procedural characteristics, and 12-month clinical outcomes in patients undergoing nonurgent PCI in Western Europe and in Asia. METHODS: We analyzed all patients enrolled in the worldwide e-HEALING (electronic Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth) registry living in Western Europe and Asia. All patients were treated with at least one endothelial progenitor cell capturing stent. The main study outcome was target vessel failure at the 12-month follow-up, defined as the composite of cardiac death or myocardial infarction and target vessel revascularization. RESULTS: A total of 3504 patients, 2873 living in Western Europe and 731 living in Asia, were assessed in the current analysis. Almost all of the baseline clinical and angiographic characteristics differed significantly between both populations. Target vessel failure at the 12-month follow-up occurred in 11.4% of the Western Europe patients and in 5.6% of the Asian patients (P<0.01). CONCLUSION: We conclude that differences exist in the baseline, angiographic, and procedural characteristics between Western European and Asian patients undergoing nonurgent PCI. In addition, the 1-year clinical outcomes differ significantly after PCI between Western European and Asian patients. Our results indicate that reports from studies performed worldwide should include both overall and regional subgroup outcomes.
Authors: Crystel M Gijsberts; Aruni Seneviratna; Imo E Hoefer; Pierfrancesco Agostoni; Saskia Z H Rittersma; Gerard Pasterkamp; Mikael Hartman; Leonardo Pinto de Carvalho; A Mark Richards; Folkert W Asselbergs; Dominique P V de Kleijn; Mark Y Chan Journal: PLoS One Date: 2015-07-06 Impact factor: 3.240
Authors: Crystel M Gijsberts; Aruni Seneviratna; Leonardo P de Carvalho; Hester M den Ruijter; Puwalani Vidanapthirana; Vitaly Sorokin; Pieter Stella; Pierfrancesco Agostoni; Folkert W Asselbergs; A Mark Richards; Adrian F Low; Chi-Hang Lee; Huay Cheem Tan; Imo E Hoefer; Gerard Pasterkamp; Dominique P V de Kleijn; Mark Y Chan Journal: PLoS One Date: 2015-07-06 Impact factor: 3.240
Authors: Florian Krackhardt; Matthias Waliszewski; Wan Azman Wan Ahmad; Viktor Kočka; Petr Toušek; Bronislav Janek; Milan Trenčan; Peter Krajči; Fernando Lozano; Koldobika Garcia-San Roman; Imanol Otaegui Irurueta; Bruno Garcia Del Blanco; Lucie Wachowiak; Victoria Vilalta Del Olmo; Eduard Fernandez Nofrerías; Myung Ho Jeong; Byung-Chun Jung; Kyu-Rock Han; Christophe Piot; Laurent Sebagh; Jérôme Rischner; Michel Pansieri; Matthias Leschke; Tae Hoon Ahn Journal: PLoS One Date: 2020-01-13 Impact factor: 3.240
Authors: Hee Hwa Ho; Dasdo Antonius Sinaga; Mohd Kamal Mohd Arshad; Sazzli Kasim; Jin Hyun Lee; Deanna Zhi Lin Khoo; Kwok Kong Loh; Fahim Haider Jafary; Paul Jau Lueng Ong; Simon Soo Siong Lo Journal: Int J Cardiol Heart Vasc Date: 2020-01-23