The effects of a multifunctional oligomer and its incorporation strategies on the gene delivery efficiency of poly(L-lysine).

A novel multifunctional oligomer is synthesized and incorporated to enhance the gene delivery efficiency of PLL via non-electrostatic assembly and covalent grafting strategies. The improvement of the gene delivery efficiency is dependent on the gene carrying complex properties, and the properties are dependent on the oligomer incorporation strategy. This journal is © The Royal Society of Chemistry 2012