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Literature DB >> 22472616

Turning Dicer on its head.

Abstract

Recent structural analysis of full-length human Dicer supports a new model of the enzyme's domain arrangement and provides a structural basis for many of Dicer's biochemical attributes.

Entities: Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22472616 DOI： 10.1038/nsmb.2275

Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369

14 in total

1. Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.

Authors: Takashi Sasaki; Nobuyoshi Shimizu
Journal: Gene Date: 2007-04-06 Impact factor: 3.688

2. Dicer's helicase domain is required for accumulation of some, but not all, C. elegans endogenous siRNAs.

Authors: Noah C Welker; Derek M Pavelec; David A Nix; Thomas F Duchaine; Scott Kennedy; Brenda L Bass
Journal: RNA Date: 2010-03-30 Impact factor: 4.942

3. Structural basis for double-stranded RNA processing by Dicer.

Authors: Ian J Macrae; Kaihong Zhou; Fei Li; Adrian Repic; Angela N Brooks; W Zacheus Cande; Paul D Adams; Jennifer A Doudna
Journal: Science Date: 2006-01-13 Impact factor: 47.728

4. Recognition of the pre-miRNA structure by Drosophila Dicer-1.

Authors: Akihisa Tsutsumi; Tomoko Kawamata; Natsuko Izumi; Hervé Seitz; Yukihide Tomari
Journal: Nat Struct Mol Biol Date: 2011-09-18 Impact factor: 15.369

5. Dicer's helicase domain discriminates dsRNA termini to promote an altered reaction mode.

Authors: Noah C Welker; Tuhin S Maity; Xuecheng Ye; P Joseph Aruscavage; Ammie A Krauchuk; Qinghua Liu; Brenda L Bass
Journal: Mol Cell Date: 2011-03-04 Impact factor: 17.970

6. Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease.

Authors: Elif Sarinay Cenik; Ryuya Fukunaga; Gang Lu; Robert Dutcher; Yeming Wang; Traci M Tanaka Hall; Phillip D Zamore
Journal: Mol Cell Date: 2011-03-17 Impact factor: 17.970

7. Structure of the human Dicer-TRBP complex by electron microscopy.

Authors: Pick-Wei Lau; Clinton S Potter; Bridget Carragher; Ian J MacRae
Journal: Structure Date: 2009-10-14 Impact factor: 5.006

8. Autoinhibition of human dicer by its internal helicase domain.

Authors: Enbo Ma; Ian J MacRae; Jack F Kirsch; Jennifer A Doudna
Journal: J Mol Biol Date: 2008-05-08 Impact factor: 5.469

9. Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein-protein interaction.

Authors: Haina Qin; Fading Chen; Xuelu Huan; Satoru Machida; Jianxing Song; Y Adam Yuan
Journal: RNA Date: 2010-01-27 Impact factor: 4.942

10. Structural insights into RNA processing by the human RISC-loading complex.

Authors: Hong-Wei Wang; Cameron Noland; Bunpote Siridechadilok; David W Taylor; Enbo Ma; Karin Felderer; Jennifer A Doudna; Eva Nogales
Journal: Nat Struct Mol Biol Date: 2009-10-11 Impact factor: 15.369

1 in total

1. The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo.

Authors: Shuo Gu; Lan Jin; Yue Zhang; Yong Huang; Feijie Zhang; Paul N Valdmanis; Mark A Kay
Journal: Cell Date: 2012-11-09 Impact factor: 41.582

1 in total