Literature DB >> 22472314

Human-animal anthrax outbreak in the Luangwa valley of Zambia in 2011.

Mudenda B Hang'ombe1, James C L Mwansa, Sergio Muwowo, Phillip Mulenga, Muzala Kapina, Eric Musenga, David Squarre, Liywali Mataa, Suzuki Y Thomas, Hirohito Ogawa, Hirofumi Sawa, Hideaki Higashi.   

Abstract

There has been a reduction of incidences of anthrax in the developed countries but it is still a public health problem in the developing countries where communities live in interface areas with wildlife. An outbreak of anthrax in Hippopotamus amphibious was observed in Zambia. Following the death of hippopotamuses, suspected human cases were reported. The objective of this study was to isolate and confirm Bacillus anthracis and to determine the antimicrobial susceptibility for the management of the disease. Of the specimens collected, 29.4% (95% confidence interval [CI], 11.4-56.0) were from humans, 42.1% (95% CI, 21.1-66.0) were from hippopotamuses and 20.0% (95% CI, 6.61-44.3) from the soil were found to be positive were for B. anthracis. An antimicrobial susceptibility test revealed that all the isolates were found to be sensitive to the recommended antibiotics. The disease control was achieved by case management and by explaining to the communities that they should avoid contact with animals that die from unknown causes.

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Year:  2012        PMID: 22472314     DOI: 10.1258/td.2012.110454

Source DB:  PubMed          Journal:  Trop Doct        ISSN: 0049-4755            Impact factor:   0.731


  13 in total

1.  Serodiagnosis of human cutaneous anthrax in India using an indirect anti-lethal factor IgG enzyme-linked immunosorbent assay.

Authors:  N Ghosh; I Tomar; H Lukka; A K Goel
Journal:  Clin Vaccine Immunol       Date:  2012-12-26

2.  A novel multiplex PCR discriminates Bacillus anthracis and its genetically related strains from other Bacillus cereus group species.

Authors:  Hirohito Ogawa; Daisuke Fujikura; Miyuki Ohnuma; Naomi Ohnishi; Bernard M Hang'ombe; Hitomi Mimuro; Takayuki Ezaki; Aaron S Mweene; Hideaki Higashi
Journal:  PLoS One       Date:  2015-03-16       Impact factor: 3.240

3.  Bacillus cereus from the environment is genetically related to the highly pathogenic B. cereus in Zambia.

Authors:  Hirohito Ogawa; Miyuki Ohnuma; David Squarre; Aaron Simanyengwe Mweene; Takayuki Ezaki; Daisuke Fujikura; Naomi Ohnishi; Yuka Thomas; Bernard Mudenda Hang'ombe; Hideaki Higashi
Journal:  J Vet Med Sci       Date:  2015-03-23       Impact factor: 1.267

4.  Genome Sequence of a Bacillus anthracis Outbreak Strain from Zambia, 2011.

Authors:  Naomi Ohnishi; Fumito Maruyama; Hirohito Ogawa; Hirokazu Kachi; Shunsuke Yamada; Daisuke Fujikura; Ichiro Nakagawa; Mudenda B Hang'ombe; Yuka Thomas; Aaron S Mweene; Hideaki Higashi
Journal:  Genome Announc       Date:  2014-03-06

5.  Comparison of French and Worldwide Bacillus anthracis Strains Favors a Recent, Post-Columbian Origin of the Predominant North-American Clade.

Authors:  Gilles Vergnaud; Guillaume Girault; Simon Thierry; Christine Pourcel; Nora Madani; Yann Blouin
Journal:  PLoS One       Date:  2016-02-22       Impact factor: 3.240

6.  ANTXR-1 and -2 independent modulation of a cytotoxicity mediated by anthrax toxin in human cells.

Authors:  Daisuke Fujikura; Kochi Toyomane; Kozue Kamiya; Memi Mutoh; Etsuko Mifune; Miyuki Ohnuma; Hideaki Higashi
Journal:  J Vet Med Sci       Date:  2016-05-12       Impact factor: 1.267

Review 7.  Anthrax outbreaks in the humans - livestock and wildlife interface areas of Northern Tanzania: a retrospective record review 2006-2016.

Authors:  Elibariki Reuben Mwakapeje; Sol Høgset; Robert Fyumagwa; Hezron Emmanuel Nonga; Robinson Hammerthon Mdegela; Eystein Skjerve
Journal:  BMC Public Health       Date:  2018-01-05       Impact factor: 3.295

8.  Role of Food Insecurity in Outbreak of Anthrax Infections among Humans and Hippopotamuses Living in a Game Reserve Area, Rural Zambia.

Authors:  Mark W Lehman; Allen S Craig; Constantine Malama; Muzala Kapina-Kany'anga; Philip Malenga; Fanny Munsaka; Sergio Muwowo; Sean Shadomy; Melissa A Marx
Journal:  Emerg Infect Dis       Date:  2017-09       Impact factor: 6.883

9.  Mapping the Distribution of Anthrax in Mainland China, 2005-2013.

Authors:  Wan-Jun Chen; Sheng-Jie Lai; Yang Yang; Kun Liu; Xin-Lou Li; Hong-Wu Yao; Yu Li; Hang Zhou; Li-Ping Wang; Di Mu; Wen-Wu Yin; Li-Qun Fang; Hong-Jie Yu; Wu-Chun Cao
Journal:  PLoS Negl Trop Dis       Date:  2016-04-20

10.  Development and application of a Bacillus anthracis protective antigen domain-1 in-house ELISA for the detection of anti-protective antigen antibodies in cattle in Zambia.

Authors:  Manyando Simbotwe; Daisuke Fujikura; Miyuki Ohnuma; Ryosuke Omori; Yoshikazu Furuta; Geoffrey Munkombwe Muuka; Bernard Mudenda Hang'ombe; Hideaki Higashi
Journal:  PLoS One       Date:  2018-10-18       Impact factor: 3.240

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