Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Design of a high-throughput flow perfusion bioreactor system for tissue engineering.

Literature DB >> 22468910

Design of a high-throughput flow perfusion bioreactor system for tissue engineering.

Rebecca L Dahlin¹, Ville V Meretoja, Mengwei Ni, F Kurtis Kasper, Antonios G Mikos.

Abstract

Flow perfusion culture is used in many areas of tissue engineering and offers several key advantages. However, one challenge to these cultures is the relatively low-throughput nature of perfusion bioreactors. Here, a flow perfusion bioreactor with increased throughput was designed and built for tissue engineering. This design uses an integrated medium reservoir and flow chamber in order to increase the throughput, limit the volume of medium required to operate the system, and simplify the assembly and operation.

Mesh：

Year: 2012 PMID： 22468910 PMCID： PMC3460612 DOI： 10.1089/ten.TEC.2012.0037

Source DB: PubMed Journal: Tissue Eng Part C Methods ISSN： 1937-3384 Impact factor: 3.056

11 in total

1. Comparison of chondrogensis in static and perfused bioreactor culture.

Authors: D Pazzano; K A Mercier; J M Moran; S S Fong; D D DiBiasio; J X Rulfs; S S Kohles; L J Bonassar
Journal: Biotechnol Prog Date: 2000 Sep-Oct

2. Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces.

Authors: Vassilios I Sikavitsas; Gregory N Bancroft; Heidi L Holtorf; John A Jansen; Antonios G Mikos
Journal: Proc Natl Acad Sci U S A Date: 2003-12-01 Impact factor: 11.205

3. Design of a flow perfusion bioreactor system for bone tissue-engineering applications.

Authors: Gregory N Bancroft; Vassilios I Sikavitsas; Antonios G Mikos
Journal: Tissue Eng Date: 2003-06

Review 4. Bone tissue engineering bioreactors: dynamic culture and the influence of shear stress.

Authors: Andrew B Yeatts; John P Fisher
Journal: Bone Date: 2010-10-13 Impact factor: 4.398

Review 5. Perfusion effects and hydrodynamics.

Authors: Robert A Peattie; Robert J Fisher
Journal: Adv Biochem Eng Biotechnol Date: 2007 Impact factor: 2.635

Review 6. Articular cartilage bioreactors and bioprocesses.

Authors: Eric M Darling; Kyriacos A Athanasiou
Journal: Tissue Eng Date: 2003-02

7. Bioactive polymer/extracellular matrix scaffolds fabricated with a flow perfusion bioreactor for cartilage tissue engineering.

Authors: Jiehong Liao; Xuan Guo; K Jane Grande-Allen; F Kurtis Kasper; Antonios G Mikos
Journal: Biomaterials Date: 2010-08-24 Impact factor: 12.479

8. Low-density cultures of bovine chondrocytes: effects of scaffold material and culture system.

Authors: Jerry C Hu; Kyriacos A Athanasiou
Journal: Biomaterials Date: 2005-05 Impact factor: 12.479

9. Modulation of osteogenic properties of biodegradable polymer/extracellular matrix scaffolds generated with a flow perfusion bioreactor.

Authors: Jiehong Liao; Xuan Guo; Dan Nelson; F Kurtis Kasper; Antonios G Mikos
Journal: Acta Biomater Date: 2010-01-18 Impact factor: 8.947

Review 10. Animal models for cartilage regeneration and repair.

Authors: Constance R Chu; Michal Szczodry; Stephen Bruno
Journal: Tissue Eng Part B Rev Date: 2010-02 Impact factor: 6.389

10 in total

Review 1. MRI and MRS of intact perfused cancer cell metabolism, invasion, and stromal cell interactions.

Authors: Marie-France Penet; Tariq Shah; Flonne Wildes; Balaji Krishnamachary; Santosh K Bharti; Jesus Pacheco-Torres; Dmitri Artemov; Zaver M Bhujwalla
Journal: NMR Biomed Date: 2019-01-28 Impact factor: 4.044

2. Modeling Stroma-Induced Drug Resistance in a Tissue-Engineered Tumor Model of Ewing Sarcoma.

Authors: Marco Santoro; Brian A Menegaz; Salah-Eddine Lamhamedi-Cherradi; Eric R Molina; Danielle Wu; Waldemar Priebe; Joseph A Ludwig; Antonios G Mikos
Journal: Tissue Eng Part A Date: 2017-01 Impact factor: 3.845

Review 3. Mesenchymal stem cell cultivation in electrospun scaffolds: mechanistic modeling for tissue engineering.

Authors: Ágata Paim; Isabel C Tessaro; Nilo S M Cardozo; Patricia Pranke
Journal: J Biol Phys Date: 2018-03-05 Impact factor: 1.365

4. Direct and indirect co-culture of chondrocytes and mesenchymal stem cells for the generation of polymer/extracellular matrix hybrid constructs.

Authors: Erica J Levorson; Marco Santoro; F Kurtis Kasper; Antonios G Mikos
Journal: Acta Biomater Date: 2013-12-21 Impact factor: 8.947

5. Chondrogenic phenotype of articular chondrocytes in monoculture and co-culture with mesenchymal stem cells in flow perfusion.

Authors: Rebecca L Dahlin; Ville V Meretoja; Mengwei Ni; F Kurtis Kasper; Antonios G Mikos
Journal: Tissue Eng Part A Date: 2014-06-03 Impact factor: 3.845

6. A Scalable Perfusion Culture System with Miniature Peristaltic Pumps for Live-Cell Imaging Assays with Provision for Microfabricated Scaffolds.

Authors: Sreenath Balakrishnan; M S Suma; Shilpa R Raju; Santosh D B Bhargav; S Arunima; Saumitra Das; G K Ananthasuresh
Journal: Biores Open Access Date: 2015-08-01