STUDY OBJECTIVES: The aim of the study was to investigate the effect of ambient temperature on sleep, sleep apnea, and morning alertness in patients with obstructive sleep apnea. DESIGN: Randomized controlled trial. SETTING: In-hospital investigations. PARTICIPANTS: Forty patients with obstructive sleep apnea naïve to treatment, with an apnea-hypopnea index of 10-30. INTERVENTIONS: Three different nights in room temperatures of 16°C, 20°C, and 24°C. MEASUREMENTS: Overnight polysomnography and Karolinska Sleepiness Scale. RESULTS: The obstructive apnea-hypopnea index was 30 ± 17 at 16°C room temperature, 28 ± 17 at 20°C, and 24 ± 18 at 24°C. The obstructive apnea-hypopnea index was higher at 16°C room temperature versus 24°C (P = 0.001) and at 20°C room temperature versus 24°C (P = 0.033). Total sleep time was a mean of 30 min longer (P = 0.009), mean sleep efficiency was higher (77 ± 11% versus 71 ± 13% respectively, P = 0.012), and the patients were significantly more alert according to the Karolinska Sleepiness Scale (P < 0.028) in the morning at 16°C room temperature versus 24°C. The amount of sleep in different sleep stages was not affected by room temperature. CONCLUSIONS:Untreated patients with obstructive sleep apnea sleep longer, have better sleep efficiency, and are more alert in the morning after a night's sleep at 16°C room temperature compared with 24°C, but obstructive sleep apnea is more severe at 16°C and 20°C compared with 24°C. CLINICAL TRIAL INFORMATION: This study is registered in ClinicalTrials.gov number NCT00544752.
RCT Entities:
STUDY OBJECTIVES: The aim of the study was to investigate the effect of ambient temperature on sleep, sleep apnea, and morning alertness in patients with obstructive sleep apnea. DESIGN: Randomized controlled trial. SETTING: In-hospital investigations. PARTICIPANTS: Forty patients with obstructive sleep apnea naïve to treatment, with an apnea-hypopnea index of 10-30. INTERVENTIONS: Three different nights in room temperatures of 16°C, 20°C, and 24°C. MEASUREMENTS: Overnight polysomnography and Karolinska Sleepiness Scale. RESULTS: The obstructive apnea-hypopnea index was 30 ± 17 at 16°C room temperature, 28 ± 17 at 20°C, and 24 ± 18 at 24°C. The obstructive apnea-hypopnea index was higher at 16°C room temperature versus 24°C (P = 0.001) and at 20°C room temperature versus 24°C (P = 0.033). Total sleep time was a mean of 30 min longer (P = 0.009), mean sleep efficiency was higher (77 ± 11% versus 71 ± 13% respectively, P = 0.012), and the patients were significantly more alert according to the Karolinska Sleepiness Scale (P < 0.028) in the morning at 16°C room temperature versus 24°C. The amount of sleep in different sleep stages was not affected by room temperature. CONCLUSIONS: Untreated patients with obstructive sleep apnea sleep longer, have better sleep efficiency, and are more alert in the morning after a night's sleep at 16°C room temperature compared with 24°C, but obstructive sleep apnea is more severe at 16°C and 20°C compared with 24°C. CLINICAL TRIAL INFORMATION: This study is registered in ClinicalTrials.gov number NCT00544752.
Authors: T Hori; Y Sugita; E Koga; S Shirakawa; K Inoue; S Uchida; H Kuwahara; M Kousaka; T Kobayashi; Y Tsuji; M Terashima; K Fukuda; N Fukuda Journal: Psychiatry Clin Neurosci Date: 2001-06 Impact factor: 5.188
Authors: Lauren Hale; Terrence D Hill; Elliot Friedman; F Javier Nieto; Loren W Galvao; Corinne D Engelman; Kristen M C Malecki; Paul E Peppard Journal: Soc Sci Med Date: 2012-08-07 Impact factor: 4.634
Authors: Laurens Reinke; Marjolein Haveman; Sandra Horsten; Thomas Falck; Esther M van der Heide; Sander Pastoor; Johannes H van der Hoeven; Anthony R Absalom; Jaap E Tulleken Journal: J Sleep Res Date: 2019-12-13 Impact factor: 3.981