Literature DB >> 22466951

Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure.

Qing-You Yang1, Ke-Ji Chen, Shu Lu, Hui-Ru Sun.   

Abstract

This paper reviewed the retrieved literature published in the last 10 years, regarding the mechanism of Radix Astragalus in treating heart failure, in aspects of myocardial contraction improvement, cardiac muscle cell protection, neuro-endocrinal system regulation, relative cytokine regulation, and left ventricular remodeling inhibition, etc.

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Year:  2012        PMID： 22466951     DOI： 10.1007/s11655-012-1022-1

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN： 1672-0415            Impact factor:   1.978


  17 in total

Review 1.  Toward biologically targeted therapy of calcium cycling defects in heart failure.

Authors:  Yasuhiro Ikeda; Masahiko Hoshijima; Kenneth R Chien
Journal:  Physiology (Bethesda)       Date:  2008-02

2.  Astragaloside IV dilates aortic vessels from normal and spontaneously hypertensive rats through endothelium-dependent and endothelium-independent ways.

Authors:  Wei-Dong Zhang; Chuan Zhang; Xu-Hui Wang; Ping-Jin Gao; Ding-Liang Zhu; Hong Chen; Run-Hui Liu; Hui-Liang Li
Journal:  Planta Med       Date:  2006-05-29       Impact factor: 3.352

3.  Evidence for enhanced free radical activity in chronic congestive heart failure secondary to coronary artery disease.

Authors:  J McMurray; J McLay; M Chopra; A Bridges; J J Belch
Journal:  Am J Cardiol       Date:  1990-05-15       Impact factor: 2.778

4.  Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy.

Authors:  J Narula; P Pandey; E Arbustini; N Haider; N Narula; F D Kolodgie; B Dal Bello; M J Semigran; A Bielsa-Masdeu; G W Dec; S Israels; M Ballester; R Virmani; S Saxena; S Kharbanda
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

5.  Effect of astragalosides on intracellular calcium overload in cultured cardiac myocytes of neonatal rats.

Authors:  Dan Meng; Xiang-Jian Chen; Yun-Yun Bian; Ping Li; Di Yang; Ji-Nan Zhang
Journal:  Am J Chin Med       Date:  2005       Impact factor: 4.667

6.  Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats.

Authors:  Zi-Pu Li; Qian Cao
Journal:  Acta Pharmacol Sin       Date:  2002-10       Impact factor: 6.150

7.  Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro.

Authors:  Wei-Dong Zhang; Hong Chen; Chuan Zhang; Run-Hui Liu; Hui-Liang Li; Hong-Zhuan Chen
Journal:  Planta Med       Date:  2006-01       Impact factor: 3.352

8.  Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings.

Authors:  Chuan Zhang; Xu-Hui Wang; Mei-Fang Zhong; Run-Hui Liu; Hui-Liang Li; Wei-Dong Zhang; Hong Chen
Journal:  Clin Exp Pharmacol Physiol       Date:  2007 May-Jun       Impact factor: 2.557

9.  Protective effect of astragalosides on myocardial injury by isoproterenol in SD rats.

Authors:  Xiang-Jian Chen; Dan Meng; Lin Feng; Yun-Yun Bian; Ping Li; Di Yang; Ke-Jiang Cao; Ji-Nan Zhang
Journal:  Am J Chin Med       Date:  2006       Impact factor: 4.667

10.  [Effects of Astragalus membranaceus on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action].

Authors:  L X Chen; J Z Liao; W Q Guo
Journal:  Zhongguo Zhong Xi Yi Jie He Za Zhi       Date:  1995-03
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  8 in total

1.  Protective effects of Radix Astragali injection on multiple organs of rats with obstructive jaundice.

Authors:  Zhe-Wei Fei; Xi-Ping Zhang; Jie Zhang; Xin-Mei Huang; Di-Jiong Wu; Hong-Hao Bi
Journal:  Chin J Integr Med       Date:  2015-04-06       Impact factor: 1.978

2.  In Silico Prediction of Molecular Targets of Astragaloside IV for Alleviation of COVID-19 Hyperinflammation by Systems Network Pharmacology and Bioinformatic Gene Expression Analysis.

Authors:  Chenliang Ge; Yan He
Journal:  Front Pharmacol       Date:  2020-09-16       Impact factor: 5.810

3.  High-throughput metabolomics for evaluating the efficacy and discovering the metabolic mechanism of Luozhen capsules from the excessive liver-fire syndrome of hypertension.

Authors:  Xi-Jun Wang; Xin Gao; Ai-Hua Zhang; Fang-Fang Wu; Guang-Li Yan; Hui Sun
Journal:  RSC Adv       Date:  2019-10-09       Impact factor: 4.036

4.  Blood stasis syndrome of coronary heart disease: A perspective of modern medicine.

Authors:  Gui Yu; Jie Wang
Journal:  Chin J Integr Med       Date:  2013-07-27       Impact factor: 1.978

5.  Improved medical expenditure and survival with integration of traditional Chinese medicine treatment in patients with heart failure: A nationwide population-based cohort study.

Authors:  Ming-Yen Tsai; Wen-Long Hu; Jen-Huai Chiang; Yu-Chuen Huang; Shih-Yu Chen; Yu-Chiang Hung; Yung-Hsiang Chen
Journal:  Oncotarget       Date:  2017-08-08

Review 6.  Evaluation of the Pharmaceutical Properties and Value of Astragali Radix.

Authors:  Amy G W Gong; Ran Duan; Huai Y Wang; Xiang P Kong; Tina T X Dong; Karl W K Tsim; Kelvin Chan
Journal:  Medicines (Basel)       Date:  2018-05-21

7.  Puerarin attenuates isoproterenol‑induced myocardial hypertrophy via inhibition of the Wnt/β‑catenin signaling pathway.

Authors:  Xiaoying Wang; Kai He; Linlin Ma; Lan Wu; Yan Yang; Yanfei Li
Journal:  Mol Med Rep       Date:  2022-08-10       Impact factor: 3.423

8.  Astragalus Granule Prevents Ca2+ Current Remodeling in Heart Failure by the Downregulation of CaMKII.

Authors:  Sinai Li; Yibing Nong; Qun Gao; Jing Liu; Yan Li; Xiaoyun Cui; Jie Wan; Jinjin Lu; Mingjie Sun; Qian Wu; Xiaolu Shi; Haifeng Cui; Weihong Liu; Mingxue Zhou; Lina Li; Qian Lin
Journal:  Evid Based Complement Alternat Med       Date:  2017-08-10       Impact factor: 2.629
  8 in total

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