Literature DB >> 22464812

Oral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: case report and review of the literature.

Filipe Vilas-Boas, Fernando Magro, Rui Balhau, José M Lopes, Francisco Beça, Catarina Eloy, Susana Lopes, Guilherme Macedo.   

Abstract

Thiopurines are widely used for remission maintenance and post-operative recurrence prevention in Crohn's disease. The increased risk of cancer in transplant recipients on azathioprine is well recognized and there are concerns that this may also be true for inflammatory bowel disease patients. We report a case of a 33-year-old Caucasian woman with Crohn's disease treated with azathioprine for 9 years who developed an ulcerated lesion at the right superior retromolar trigone. Biopsy specimen revealed a squamous cell carcinoma.
Copyright © 2012 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22464812     DOI: 10.1016/j.crohns.2012.03.004

Source DB:  PubMed          Journal:  J Crohns Colitis        ISSN: 1873-9946            Impact factor:   9.071


  4 in total

1.  Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan.

Authors:  Faezeh Khozeimeh; Hadi Shakerin; Hamed Daghaghzadeh; Fereshteh Najarzadegan; Zahra Golestannejad; Peyman Adibi
Journal:  Dent Res J (Isfahan)       Date:  2021-02-23

2.  DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib.

Authors:  Matthew Peacock; Reto Brem; Peter Macpherson; Peter Karran
Journal:  Nucleic Acids Res       Date:  2014-11-20       Impact factor: 16.971

Review 3.  Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA.

Authors:  Reto Brem; Melisa Guven; Peter Karran
Journal:  Free Radic Biol Med       Date:  2016-10-27       Impact factor: 7.376

4.  Laryngeal Carcinoma in Patients With Inflammatory Bowel Disease: Clinical Outcomes and Risk Factors.

Authors:  Steffi E M van de Ven; Lauranne A A P Derikx; Iris D Nagtegaal; Carla M van Herpen; Robert P Takes; Willem J G Melchers; Marieke Pierik; Tim van den Heuvel; Rob H A Verhoeven; Frank Hoentjen; L H C Nissen
Journal:  Inflamm Bowel Dis       Date:  2020-06-18       Impact factor: 5.325

  4 in total

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