Literature DB >> 22464439

PARP1 parylation promotes silent locus transmission in the nucleolus: the suspicion confirmed.

Maxim Isabelle1, Imed-Eddine Gallouzi, Guy G Poirier.   

Abstract

Parylation modulates various processes, including transcription. In this issue of Molecular Cell, Guetg et al. (2012) show that, in the nucleolus, PARP1-mediated parylation of TIP5 promotes the silencing of rDNA chromatin during replication, uncovering the mechanism by which PARP1 ensures that silent rDNA regions are properly inherited.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22464439     DOI： 10.1016/j.molcel.2012.03.012

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  4 in total

1.  PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner.

Authors:  Sebastian Veith; Andrea Schink; Marina Engbrecht; Matthias Mack; Lisa Rank; Pascal Rossatti; Mariam Hakobyan; Denise Goly; Tanja Hefele; Marco Frensch; Arthur Fischbach; Alexander Bürkle; Aswin Mangerich
Journal:  Sci Rep       Date:  2019-07-11       Impact factor: 4.379

2.  DNA double-strand breaks coupled with PARP1 and HNRNPA2B1 binding sites flank coordinately expressed domains in human chromosomes.

Authors:  Nickolai A Tchurikov; Olga V Kretova; Daria M Fedoseeva; Dmitri V Sosin; Sergei A Grachev; Marina V Serebraykova; Svetlana A Romanenko; Nadezhda V Vorobieva; Yuri V Kravatsky
Journal:  PLoS Genet       Date:  2013-04-04       Impact factor: 5.917

Review 3.  Post-transcriptional regulation by poly(ADP-ribosyl)ation of the RNA-binding proteins.

Authors:  Yingbiao Ji; Alexei V Tulin
Journal:  Int J Mol Sci       Date:  2013-08-05       Impact factor: 5.923

4.  Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus.

Authors:  Christian Siebenwirth; Christoph Greubel; Guido A Drexler; Judith Reindl; Dietrich W M Walsh; Benjamin Schwarz; Matthias Sammer; Iris Baur; Helmut Pospiech; Thomas E Schmid; Günther Dollinger; Anna A Friedl
Journal:  J Cell Sci       Date:  2019-10-09       Impact factor: 5.285
  4 in total

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