Literature DB >> 2246269

Mannosidase II and the 135-kDa Golgi-specific antigen recognized monoclonal antibody 53FC3 are the same dimeric protein.

M D Baron1, H Garoff.   

Abstract

Monoclonal antibodies are frequently used as organelle-specific markers without identifying the specific antigen recognized. We have purified the protein recognized by a Golgi-specific monoclonal antibody 53FC3 (Burke, B., Griffiths, G., Reggio, H., Louvard, D., and Warren, G. (1982) EMBO J. 1, 1621-1628). Peptide microsequencing suggested that this antigen is mannosidase II, which was confirmed by cross-immunoprecipitation with an anti-mannosidase II antibody and by precipitation of mannosidase activity with the monoclonal antibody. Mannosidase II was found to exist normally as a disulfide-linked dimer.

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Year:  1990        PMID: 2246269

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  16 in total

1.  The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.

Authors:  M E Greenberg; A J Iafrate; J Skowronski
Journal:  EMBO J       Date:  1998-05-15       Impact factor: 11.598

2.  Rinderpest viruses lacking the C and V proteins show specific defects in growth and transcription of viral RNAs.

Authors:  M D Baron; T Barrett
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

3.  Heterogeneity of a fluorescent tegument component in single pseudorabies virus virions and enveloped axonal assemblies.

Authors:  T del Rio; T H Ch'ng; E A Flood; S P Gross; L W Enquist
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

4.  Ethanol causes translocation of cAMP-dependent protein kinase catalytic subunit to the nucleus.

Authors:  D P Dohrman; I Diamond; A S Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-17       Impact factor: 11.205

5.  TGN38/41 recycles between the cell surface and the TGN: brefeldin A affects its rate of return to the TGN.

Authors:  B Reaves; M Horn; G Banting
Journal:  Mol Biol Cell       Date:  1993-01       Impact factor: 4.138

6.  Retrieval of TGN proteins from the cell surface requires endosomal acidification.

Authors:  R E Chapman; S Munro
Journal:  EMBO J       Date:  1994-05-15       Impact factor: 11.598

7.  Local expression and exocytosis of viral glycoproteins in multinucleated muscle cells.

Authors:  K Metsikkö; T Hentunen; K Väänänen
Journal:  J Cell Biol       Date:  1992-06       Impact factor: 10.539

8.  Differential targeting of vesicular stomatitis virus G protein and influenza virus hemagglutinin appears during myogenesis of L6 muscle cells.

Authors:  P Rahkila; V Luukela; K Väänänen; K Metsikkö
Journal:  J Cell Biol       Date:  1998-03-09       Impact factor: 10.539

9.  Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I and II.

Authors:  A Velasco; L Hendricks; K W Moremen; D R Tulsiani; O Touster; M G Farquhar
Journal:  J Cell Biol       Date:  1993-07       Impact factor: 10.539

10.  Perturbation of the morphology of the trans-Golgi network following Brefeldin A treatment: redistribution of a TGN-specific integral membrane protein, TGN38.

Authors:  B Reaves; G Banting
Journal:  J Cell Biol       Date:  1992-01       Impact factor: 10.539

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