Literature DB >> 22461557

Draft genome sequence of the nontoxigenic Clostridium difficile strain CD37.

Michael S M Brouwer1, Elaine Allan, Peter Mullany, Adam P Roberts.   

Abstract

Here we report the draft genome sequence of Clostridium difficile strain CD37, the first nontoxigenic strain sequenced. Every sequenced strain of Clostridium difficile has been shown to contain multiple different mobile genetic elements. The draft genome sequence of strain CD37 reveals the presence of two putative conjugative transposons.

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Year:  2012        PMID： 22461557      PMCID： PMC3318468          DOI： 10.1128/JB.00122-12

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  21 in total

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Journal:  Mol Microbiol       Date:  2000-06       Impact factor: 3.501

2.  Identifying bacterial genes and endosymbiont DNA with Glimmer.

Authors:  Arthur L Delcher; Kirsten A Bratke; Edwin C Powers; Steven L Salzberg
Journal:  Bioinformatics       Date:  2007-01-19       Impact factor: 6.937

3.  Velvet: algorithms for de novo short read assembly using de Bruijn graphs.

Authors:  Daniel R Zerbino; Ewan Birney
Journal:  Genome Res       Date:  2008-03-18       Impact factor: 9.043

4.  tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.

Authors:  T M Lowe; S R Eddy
Journal:  Nucleic Acids Res       Date:  1997-03-01       Impact factor: 16.971

5.  The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome.

Authors:  Mohammed Sebaihia; Brendan W Wren; Peter Mullany; Neil F Fairweather; Nigel Minton; Richard Stabler; Nicholas R Thomson; Adam P Roberts; Ana M Cerdeño-Tárraga; Hongmei Wang; Matthew T G Holden; Anne Wright; Carol Churcher; Michael A Quail; Stephen Baker; Nathalie Bason; Karen Brooks; Tracey Chillingworth; Ann Cronin; Paul Davis; Linda Dowd; Audrey Fraser; Theresa Feltwell; Zahra Hance; Simon Holroyd; Kay Jagels; Sharon Moule; Karen Mungall; Claire Price; Ester Rabbinowitsch; Sarah Sharp; Mark Simmonds; Kim Stevens; Louise Unwin; Sally Whithead; Bruno Dupuy; Gordon Dougan; Bart Barrell; Julian Parkhill
Journal:  Nat Genet       Date:  2006-06-25       Impact factor: 38.330

6.  Genetic analysis of a tetracycline resistance element from Clostridium difficile and its conjugal transfer to and from Bacillus subtilis.

Authors:  P Mullany; M Wilks; I Lamb; C Clayton; B Wren; S Tabaqchali
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7.  Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator.

Authors:  Glen P Carter; Dena Lyras; David L Allen; Kate E Mackin; Pauline M Howarth; Jennifer R O'Connor; Julian I Rood
Journal:  J Bacteriol       Date:  2007-08-10       Impact factor: 3.490

Review 8.  Clostridium difficile infection: new developments in epidemiology and pathogenesis.

Authors:  Maja Rupnik; Mark H Wilcox; Dale N Gerding
Journal:  Nat Rev Microbiol       Date:  2009-07       Impact factor: 60.633

9.  In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes.

Authors:  Michael S M Brouwer; Adam P Roberts; Peter Mullany; Elaine Allan
Journal:  Mob Genet Elements       Date:  2012-01-01

10.  Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.

Authors:  Richard A Stabler; Miao He; Lisa Dawson; Melissa Martin; Esmeralda Valiente; Craig Corton; Trevor D Lawley; Mohammed Sebaihia; Michael A Quail; Graham Rose; Dale N Gerding; Maryse Gibert; Michel R Popoff; Julian Parkhill; Gordon Dougan; Brendan W Wren
Journal:  Genome Biol       Date:  2009-09-25       Impact factor: 13.583
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  16 in total

1.  The non-toxigenic Clostridium difficile CD37 protects mice against infection with a BI/NAP1/027 type of C. difficile strain.

Authors:  Keshan Zhang; Song Zhao; Yuankai Wang; Xuejun Zhu; Hong Shen; Yugen Chen; Xingmin Sun
Journal:  Anaerobe       Date:  2015-10-13       Impact factor: 3.331

Review 2.  Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories.

Authors:  Carey-Ann D Burnham; Karen C Carroll
Journal:  Clin Microbiol Rev       Date:  2013-07       Impact factor: 26.132

Review 3.  Diversity and Evolution in the Genome of Clostridium difficile.

Authors:  Daniel R Knight; Briony Elliott; Barbara J Chang; Timothy T Perkins; Thomas V Riley
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

Review 4.  A clinical and epidemiological review of non-toxigenic Clostridium difficile.

Authors:  Mukil Natarajan; Seth T Walk; Vincent B Young; David M Aronoff
Journal:  Anaerobe       Date:  2013-05-29       Impact factor: 3.331

Review 5.  Clostridioides difficile phage biology and application.

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Review 6.  Clostridioides difficile as a Dynamic Vehicle for the Dissemination of Antimicrobial-Resistance Determinants: Review and In Silico Analysis.

Authors:  Philip Kartalidis; Anargyros Skoulakis; Katerina Tsilipounidaki; Zoi Florou; Efthymia Petinaki; George C Fthenakis
Journal:  Microorganisms       Date:  2021-06-25

7.  Susceptibility of hamsters to Clostridium difficile isolates of differing toxinotype.

Authors:  Anthony M Buckley; Janice Spencer; Lindsay M Maclellan; Denise Candlish; June J Irvine; Gillian R Douce
Journal:  PLoS One       Date:  2013-05-21       Impact factor: 3.240

8.  Analysis of a Clostridium difficile PCR ribotype 078 100 kilobase island reveals the presence of a novel transposon, Tn6164.

Authors:  Jeroen Corver; Dennis Bakker; Michael S M Brouwer; Céline Harmanus; Marjolein P Hensgens; Adam P Roberts; Len J A Lipman; Ed J Kuijper; Hans C van Leeuwen
Journal:  BMC Microbiol       Date:  2012-07-02       Impact factor: 3.605

9.  Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers.

Authors:  Michael S M Brouwer; Adam P Roberts; Haitham Hussain; Rachel J Williams; Elaine Allan; Peter Mullany
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

Review 10.  Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance.

Authors:  Priscilla A Johanesen; Kate E Mackin; Melanie L Hutton; Milena M Awad; Sarah Larcombe; Jacob M Amy; Dena Lyras
Journal:  Genes (Basel)       Date:  2015-12-21       Impact factor: 4.096
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