Literature DB >> 22461266

Complex regional pain syndrome of the pediatric lower extremity: a retrospective review.

Edwin J Harris1, Katherine E Schimka, Russell M Carlson.   

Abstract

BACKGROUND: Complex regional pain syndrome (CRPS) type 1 is a disorder of the extremities characterized by pain, edema, limited range of motion, integument changes, and vasomotor instability often after an inciting event. In the pediatric population, CRPS may be misdiagnosed, or missed entirely, as CRPS literature for this patient population is lacking.
METHODS: Twenty-seven pediatric patient medical records with the diagnosis of CRPS type 1 from the institutional and private practices of the principal investigator (E.J.H.) were reviewed for demographics, inciting event, lower-extremity clinical examination, ancillary testing, previous treatments, time to diagnosis, treatment after diagnosis, and time to resolution of symptoms.
RESULTS: Females composed 85.2% of the patient population (n = 23) (mean age of females, 11.11 years). An inciting event preceded pain in 74.1% of patients (n = 20). On physical examination, more than 50% of patients were identified as having changes in skin color and temperature, edema to the affected lower extremity, painful or decreased range of motion in affected joints, and intact lower-extremity motor function. The average time to resolution of symptoms was 6.8 weeks for the entire population.
CONCLUSIONS: Diagnosis of CRPS type 1 should be considered in a preadolescent female complaining of pain out of proportion after an inciting event with a physical examination demonstrating change in skin color, decrease in skin temperature, edema, and painful or diminished range of motion in affected joints. Prompt diagnosis can decrease the time to resolution of symptoms.

Entities:  

Mesh:

Year:  2012        PMID: 22461266     DOI: 10.7547/1020099

Source DB:  PubMed          Journal:  J Am Podiatr Med Assoc        ISSN: 1930-8264


  7 in total

Review 1.  [Pain syndrome of the musculoskeletal system in children and adolescents].

Authors:  L Höfel; N Draheim; R Häfner; J P Haas
Journal:  Z Rheumatol       Date:  2016-04       Impact factor: 1.372

2.  National Trends in the Diagnosis of CRPS after Open and Endoscopic Carpal Tunnel Release.

Authors:  Kevin Mertz; Jeremy Trunzter; Edward Wu; James Barnes; Sara L Eppler; Robin N Kamal
Journal:  J Wrist Surg       Date:  2019-02-27

3.  Rapid treatment-induced brain changes in pediatric CRPS.

Authors:  Nathalie Erpelding; Laura Simons; Alyssa Lebel; Paul Serrano; Melissa Pielech; Sanjay Prabhu; Lino Becerra; David Borsook
Journal:  Brain Struct Funct       Date:  2014-12-17       Impact factor: 3.270

4.  Hazard of complex regional pain syndrome following human papillomavirus vaccination among adolescent girls in the United States: a case-cohort analysis of insurance claims data.

Authors:  Nadja A Vielot; Sylvia Becker-Dreps
Journal:  Expert Opin Drug Saf       Date:  2019-11-08       Impact factor: 4.250

Review 5.  Inflaming the brain: CRPS a model disease to understand neuroimmune interactions in chronic pain.

Authors:  C Linnman; L Becerra; D Borsook
Journal:  J Neuroimmune Pharmacol       Date:  2012-11-29       Impact factor: 4.147

6.  Inflammatory arthritis mimicking Complex Regional Pain Syndrome (CRPS) in a child: A case report.

Authors:  Zeliha Egilmez; Selin Turan Turgut; Afitap Icagasioglu; Irem Bicakci
Journal:  North Clin Istanb       Date:  2016-04-04

7.  Transient and persistent pain induced connectivity alterations in pediatric complex regional pain syndrome.

Authors:  Clas Linnman; Lino Becerra; Alyssa Lebel; Charles Berde; P Ellen Grant; David Borsook
Journal:  PLoS One       Date:  2013-03-19       Impact factor: 3.240

  7 in total

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