Literature DB >> 22461162

Surgical approach to bone healing in osteoporosis.

Vito Pesce1, Domenico Speciale, Giulio Sammarco, Silvio Patella, Antonio Spinarelli, Vittorio Patella.   

Abstract

Osteoporotic fractures represent one of the most common cause of disability and one of the major voice in the health economic budget in many countries of the world. Fragility fractures are especially meta-epiphyseal fractures, in skeletal sites with particular biomechanic characteristic (hip, vertebrae), complex and with more fragments, with slow healing process (mineralization and remodeling) and co-morbidity. The healing of a fracture in osteoporotic bone passes through the normal stages and concludes with union of the fracture although the healing process is prolonged. Fractures in the elderly osteoporotic patients represent a challenge to the orthopaedic surgeons. Osteoporosis does not only increase the risk of fracture but also represents a problem in osteofixation of fractures in fracture treatment. The major technical problem that surgeons face, is the difficulty to obtain a stable fixation of an implant due to osteoporotic bone. The load transmitted at the bone-implant interface can often exceed the reduced strain tolerance of osteoporotic bone.IN THE TREATMENT OF OSTEOPOROTIC FRACTURES IT IS IMPORTANT TO CONSIDER DIFFERENT ASPECTS: general conditions of elderly patient and comorbidity, the reduced muscular and bone mass and the increased bone fragility, structural modifications as medullary expansion.The aim of surgical treatment is to obtain a stable fixation that reduces pain and permits an early mobilization.

Entities:  

Year:  2009        PMID: 22461162      PMCID: PMC2781233     

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


  65 in total

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6.  Improvement of the bone-pin interface strength in osteoporotic bone with use of hydroxyapatite-coated tapered external-fixation pins. A prospective, randomized clinical study of wrist fractures.

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Journal:  J Bone Joint Surg Am       Date:  2001-05       Impact factor: 5.284

7.  Fixation of fractures of the proximal humerus with the PlantTan Humerus Fixator Plate: early experience with a new implant.

Authors:  Christophe Sadowski; Nicolas Riand; Richard Stern; Pierre Hoffmeyer
Journal:  J Shoulder Elbow Surg       Date:  2003 Mar-Apr       Impact factor: 3.019

8.  The external fixator compared with the sliding hip screw for pertrochanteric fractures of the femur.

Authors:  I C Vossinakis; L S Badras
Journal:  J Bone Joint Surg Br       Date:  2002-01

9.  Treatment of proximal humeral fractures with Polarus nail fixation.

Authors:  Julie Agel; Clifford B Jones; Anthony G Sanzone; Matthew Camuso; M Bradford Henley
Journal:  J Shoulder Elbow Surg       Date:  2004 Mar-Apr       Impact factor: 3.019

Review 10.  Locking plates in proximal humerus fractures.

Authors:  P C Strohm; P Helwig; G Konrad; N P Südkamp
Journal:  Acta Chir Orthop Traumatol Cech       Date:  2007-12       Impact factor: 0.531

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  13 in total

1.  Titanium scaffold osteogenesis in healthy and osteoporotic rats is improved by the use of low-level laser therapy (GaAlAs).

Authors:  Luana Marotta Reis de Vasconcellos; Mary Anne Moreira Barbara; Emanuel da Silva Rovai; Mariana de Oliveira França; Zahra Fernandes Ebrahim; Luis Gustavo Oliveira de Vasconcellos; Camila Deco Porto; Carlos Alberto Alves Cairo
Journal:  Lasers Med Sci       Date:  2016-04-07       Impact factor: 3.161

Review 2.  Clinical Management of Osteoporotic Fractures.

Authors:  Adam Z Khan; Richard D Rames; Anna N Miller
Journal:  Curr Osteoporos Rep       Date:  2018-06       Impact factor: 5.096

3.  Interaction between immobilized polyelectrolyte complex nanoparticles and human mesenchymal stromal cells.

Authors:  Beatrice Woltmann; Bernhard Torger; Martin Müller; Ute Hempel
Journal:  Int J Nanomedicine       Date:  2014-05-08

4.  Autograft transfer from the ipsilateral femoral condyle in depressed tibial plateau fractures.

Authors:  N K Sferopoulos
Journal:  Open Orthop J       Date:  2014-09-30

5.  Use of screw locking elements improves radiological and biomechanical results of femoral osteotomies.

Authors:  Gerardo L Garcés; Oliver Rodríguez; Enrique Rodríguez Grau-Bassas; Syra Roiz; Alejandro Yánez; Alberto Cuadrado
Journal:  BMC Musculoskelet Disord       Date:  2014-11-21       Impact factor: 2.362

6.  Strontium ranelate improves the interaction of osteoblastic cells with titanium substrates: Increase in cell proliferation, differentiation and matrix mineralization.

Authors:  William Querido; Marcos Farina; Karine Anselme
Journal:  Biomatter       Date:  2015

Review 7.  Biomimetics of Bone Implants: The Regenerative Road.

Authors:  Elizabeth Brett; John Flacco; Charles Blackshear; Michael T Longaker; Derrick C Wan
Journal:  Biores Open Access       Date:  2017-01-01

Review 8.  Design and Biological Evaluation of Delivery Systems Containing Bisphosphonates.

Authors:  Blessing Aderibigbe; Isiaka Aderibigbe; Patricia Popoola
Journal:  Pharmaceutics       Date:  2016-12-26       Impact factor: 6.321

9.  Evaluation of locked plate in the osteosynthesis of fractures in osteoporotic bones.

Authors:  Muhammad Oboirien; Stephen Patrick Agbo; Lukman Olalekan Ajiboye
Journal:  Ann Afr Med       Date:  2017 Jul-Sep

10.  Biomechanical Behavior of a Variable Angle Locked Tibiotalocalcaneal Construct.

Authors:  Farah Hamandi; Gerard Simon; Richard Laughlin; Tarun Goswami
Journal:  Bioengineering (Basel)       Date:  2020-03-14
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