Literature DB >> 22460109

Defining rewardable innovation in drug therapy.

Jeffrey K Aronson1, Robin E Ferner, Dyfrig A Hughes.   

Abstract

Implementing mechanisms for rewarding those who introduce innovative medicinal products requires a definition of 'rewardable innovation'. Here, we propose a definition of innovation with respect to medicinal products, accompanied by a ranking of the importance of different types of innovativeness, with the aim of providing a basis for rewarding such innovation.

Mesh:

Year:  2012        PMID: 22460109     DOI: 10.1038/nrd3715

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  3 in total

1.  Something new every day: defining innovation and innovativeness in drug therapy.

Authors:  Jeffrey K Aronson
Journal:  J Ambul Care Manage       Date:  2008 Jan-Mar

2.  NICE and new: appraising innovation.

Authors:  Robin E Ferner; Dyfrig A Hughes; Jeffrey K Aronson
Journal:  BMJ       Date:  2010-01-05

3.  Value-based pricing: incentive for innovation or zero net benefit?

Authors:  Dyfrig A Hughes
Journal:  Pharmacoeconomics       Date:  2011-09       Impact factor: 4.981

  3 in total
  11 in total

1.  Innovation and value-driven engineering.

Authors:  Frank L Douglas
Journal:  Nat Rev Drug Discov       Date:  2012-04-30       Impact factor: 84.694

2.  Innovation in orthopaedic surgery as it relates to evidence-based practice.

Authors:  M Hofbauer; B Muller; C D Murawski; J Karlsson; Freddie H Fu
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-03       Impact factor: 4.342

3.  Do the EMA accelerated assessment procedure and the FDA priority review ensure a therapeutic added value? 2006-2015: a cohort study.

Authors:  Denis Boucaud-Maitre; Jean-Jacques Altman
Journal:  Eur J Clin Pharmacol       Date:  2016-07-29       Impact factor: 2.953

4.  Using GRADE methodology to assess innovation of new medicinal products in Italy.

Authors:  Filomena Fortinguerra; Giovanni Tafuri; Francesco Trotta; Antonio Addis
Journal:  Br J Clin Pharmacol       Date:  2019-11-21       Impact factor: 4.335

5.  Patterns and predictors of physician adoption of new cardiovascular drugs.

Authors:  Timothy S Anderson; Wei-Hsuan Lo-Ciganic; Walid F Gellad; Rouxin Zhang; Haiden A Huskamp; Niteesh K Choudhry; Chung-Chou H Chang; Seth Richards-Shubik; Hasan Guclu; Bobby Jones; Julie M Donohue
Journal:  Healthc (Amst)       Date:  2017-10-21

Review 6.  The most transformative drugs of the past 25 years: a survey of physicians.

Authors:  Aaron S Kesselheim; Jerry Avorn
Journal:  Nat Rev Drug Discov       Date:  2013-05-17       Impact factor: 84.694

7.  How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001-2012.

Authors:  Derek J Ward; Angharad Slade; Tracey Genus; Orsolina I Martino; Andrew J Stevens
Journal:  BMJ Open       Date:  2014-10-24       Impact factor: 2.692

Review 8.  Adaptive Pathways: Possible Next Steps for Payers in Preparation for Their Potential Implementation.

Authors:  Patricia Vella Bonanno; Michael Ermisch; Brian Godman; Antony P Martin; Jesper Van Den Bergh; Liudmila Bezmelnitsyna; Anna Bucsics; Francis Arickx; Alexander Bybau; Tomasz Bochenek; Marc van de Casteele; Eduardo Diogene; Irene Eriksson; Jurij Fürst; Mohamed Gad; Ieva Greičiūtė-Kuprijanov; Martin van der Graaff; Jolanta Gulbinovic; Jan Jones; Roberta Joppi; Marija Kalaba; Ott Laius; Irene Langner; Ileana Mardare; Vanda Markovic-Pekovic; Einar Magnusson; Oyvind Melien; Dmitry O Meshkov; Guenka I Petrova; Gisbert Selke; Catherine Sermet; Steven Simoens; Ad Schuurman; Ricardo Ramos; Jorge Rodrigues; Corinne Zara; Eva Zebedin-Brandl; Alan Haycox
Journal:  Front Pharmacol       Date:  2017-08-23       Impact factor: 5.810

9.  Trends in the costs of drugs launched in the UK between 1981 and 2015: an analysis of the launch price of drugs in five disease areas.

Authors:  Derek J Ward; Lucy Doos; Andrew Stevens
Journal:  BMJ Open       Date:  2019-05-05       Impact factor: 2.692

Review 10.  Me-too pharmaceutical products: History, definitions, examples, and relevance to drug shortages and essential medicines lists.

Authors:  Jeffrey K Aronson; A Richard Green
Journal:  Br J Clin Pharmacol       Date:  2020-05-13       Impact factor: 4.335

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