| Literature DB >> 22459238 |
W J McMeniman1, R B Chard, J Norrie, J Posen.
Abstract
This patient presented for emergency cardiac surgery following two episodes of thrombocytopaenia, one before and one associated with exposure to unfractionated heparin in a seven-week period of intensive care management. Although the diagnosis of heparin induced thrombocytopaenia (HIT) was uncertain on clinical grounds when assessed by current criteria, the positive antibody status directed management in accordance with the internationally recognised guidelines published by the American College of Chest Physicians (ACCP) Evidence-based Clinical Practice Guidelines. An alternative anticoagulant to unfractionated heparin was indicated for cardiopulmonary bypass. Bivalirudin was selected because of recent literature supporting its safe use.Entities:
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Year: 2012 PMID: 22459238 DOI: 10.1016/j.hlc.2012.02.005
Source DB: PubMed Journal: Heart Lung Circ ISSN: 1443-9506 Impact factor: 2.975