Literature DB >> 22458565

Human parvovirus PARV4 in plasma pools of Chinese origin.

Y-Y Ma1, Y Guo, X Zhao, Z Wang, M-M Lv, Q-P Yan, J-G Zhang.   

Abstract

Human parvovirus 4 (PARV4) is present in blood and blood products. As the presence and levels of PARV4 in Chinese source plasma pools have never been determined, we implemented real-time quantitative PCR to investigate the presence of PARV4 in source plasma pools in China. Results showed that 26·15% (51/195) of lots tested positive for PARV4. The amounts of DNA ranged from 2·83 × 10(3) copies/ml to 2·35×10(7) copies/ml plasma. The high level of PARV4 in plasma pools may pose a potential risk to recipients. Further studies on the pathogenesis of PARV4 are urgently required.
© 2012 The Author(s). Vox Sanguinis © 2012 International Society of Blood Transfusion.

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Year:  2012        PMID： 22458565     DOI： 10.1111/j.1423-0410.2012.01605.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN： 0042-9007            Impact factor:   2.144


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