Literature DB >> 22458466

Conflicts among multinational ethical and scientific standards for clinical trials of therapeutic interventions.

Jacob M Kolman1, Nelda P Wray, Carol M Ashton, Danielle M Wenner, Anna F Jarman, Baruch A Brody.   

Abstract

Utilizing a sorted compendium of international clinical trial standards, investigators identified 15 conflicts among ethical and methodological guidance. Analysis distinguishes interpretational issues, lack of clarity, and contradiction as factors to be addressed if international trial guidance is to be improved.
© 2012 American Society of Law, Medicine & Ethics, Inc.

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Mesh：

Year:  2012        PMID： 22458466      PMCID： PMC3567849          DOI： 10.1111/j.1748-720X.2012.00649.x

Source DB:  PubMed          Journal:  J Law Med Ethics        ISSN： 1073-1105            Impact factor:   1.718


  17 in total

1.  What makes clinical research ethical?

Authors:  E J Emanuel; D Wendler; C Grady
Journal:  JAMA       Date:  2000 May 24-31       Impact factor: 56.272

2.  Placebo-controlled trials and the logic of clinical purpose.

Authors:  Benjamin Freedman
Journal:  IRB       Date:  1990 Nov-Dec

3.  Research involving the homeless: arguments against payment-in-kind (PinK).

Authors:  Toby L Schonfeld; Joseph S Brown; Meaghann Weniger; Bruce Gordon
Journal:  IRB       Date:  2003 Sep-Oct

Review 4.  Towards evidence based bioethics.

Authors:  Scott D Halpern
Journal:  BMJ       Date:  2005-10-15

Review 5.  The reporting of randomized clinical trials using a surgical intervention is in need of immediate improvement: a systematic review.

Authors:  Isabelle Jacquier; Isabelle Boutron; David Moher; Carine Roy; Philippe Ravaud
Journal:  Ann Surg       Date:  2006-11       Impact factor: 12.969

6.  Standards of reporting of randomized controlled trials in general surgery: can we do better?

Authors:  Sabapathy P Balasubramanian; Martin Wiener; Zeiad Alshameeri; Ravindranath Tiruvoipati; Diana Elbourne; Malcolm W Reed
Journal:  Ann Surg       Date:  2006-11       Impact factor: 12.969

7.  Methodologic standards in surgical trials.

Authors:  J C Hall; B Mills; H Nguyen; J L Hall
Journal:  Surgery       Date:  1996-04       Impact factor: 3.982

Review 8.  Methodological quality and reporting of ethical requirements in clinical trials.

Authors:  M Ruiz-Canela; J de Irala-Estevez; M A Martínez-González; E Gómez-Gracia; J Fernández-Crehuet
Journal:  J Med Ethics       Date:  2001-06       Impact factor: 2.903

Review 9.  Review of randomised trials using the post-randomised consent (Zelen's) design.

Authors:  Joy Adamson; Sarah Cockayne; Suezann Puffer; David J Torgerson
Journal:  Contemp Clin Trials       Date:  2006-02-07       Impact factor: 2.226

10.  The continuing unethical conduct of underpowered clinical trials.

Authors:  Scott D Halpern; Jason H T Karlawish; Jesse A Berlin
Journal:  JAMA       Date:  2002-07-17       Impact factor: 56.272
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  1 in total

1.  What do international ethics guidelines say in terms of the scope of medical research ethics?

Authors:  Rosemarie D L C Bernabe; Ghislaine J M W van Thiel; Johannes J M van Delden
Journal:  BMC Med Ethics       Date:  2016-04-26       Impact factor: 2.652
  1 in total

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