Literature DB >> 22457134

The theory of homogeny of liver and kidney in the treatment of kidney and liver fibrosis.

Ping Li1, Hao-Jun Zhang, Liu-Tao Zheng.   

Abstract

Chronic kidney disease (CKD) and chronic liver disease are both very harmful to human health almost all over the world, which lead to the fibrosis of the two organs ultimately. Currently, there are few satisfactory therapeutic methods in treating the two diseases. Some research works from Chinese medicine and Western medicine were done in the area recently, the results showed that kidney and liver fibrosis shared similar biological signals and events such as epithelial-mesenchymal transition (EMT) and transforming growth factor β 1, the same herbal mesenchymal medicine exhibited significantly improving effects on both liver fibrosis and kidney fibrosis by involving similar mechanism. This coincides with the theory of homogeny of Liver (Gan) and Kidney (Shen) of Chinese medicine. It would provides new clues in exploring the treatment of liver fibrosis and kidney fibrosis.

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Year:  2012        PMID: 22457134     DOI: 10.1007/s11655-012-1063-5

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  10 in total

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2.  Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

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Review 4.  Topical herbal application as an adjuvant treatment for chronic kidney disease--a systematic review of randomized controlled clinical trials.

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5.  Therapeutic mechanism of Saikosaponin-d in anti-Thy1 mAb 1-22-3-induced rat model of glomerulonephritis.

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6.  Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins.

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Journal:  Nephrology (Carlton)       Date:  2007-10       Impact factor: 2.506

7.  Pro-fibrogenic potential of PDGF-D in liver fibrosis.

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8.  Mechanism of saikosaponin-d in the regulation of rat mesangial cell proliferation and synthesis of extracellular matrix proteins.

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Journal:  Biochem Cell Biol       Date:  2007-04       Impact factor: 3.626

9.  Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury.

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10.  Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.

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  10 in total
  3 in total

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Journal:  Chin J Integr Med       Date:  2014-12-09       Impact factor: 1.978

2.  Difference of Liver and Kidney Metabolic Profiling in Chronic Atrophic Gastritis Rats between Acupuncture and Moxibustion Treatment.

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Journal:  Evid Based Complement Alternat Med       Date:  2018-09-17       Impact factor: 2.629

3.  Research and application of herbal medicine in the treatment of chronic kidney disease since the 21st century: A visualized bibliometric analysis.

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  3 in total

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