Literature DB >> 22456316

Cross-species ChIP-seq studies provide insights into regulatory strategies of PPARγ in adipocytes.

Søren F Schmidt1, Mette Jørgensen, Albin Sandelin, Susanne Mandrup.   

Abstract

Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22456316      PMCID： PMC3679271          DOI： 10.4161/trns.3.1.19302

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  24 in total

Review 1.  Transcriptional networks and chromatin remodeling controlling adipogenesis.

Authors:  Rasmus Siersbæk; Ronni Nielsen; Susanne Mandrup
Journal:  Trends Endocrinol Metab       Date:  2011-11-11       Impact factor: 12.015

Review 2.  Transcription factor binding variation in the evolution of gene regulation.

Authors:  Robin D Dowell
Journal:  Trends Genet       Date:  2010-09-23       Impact factor: 11.639

Review 3.  Forming functional fat: a growing understanding of adipocyte differentiation.

Authors:  Ana G Cristancho; Mitchell A Lazar
Journal:  Nat Rev Mol Cell Biol       Date:  2011-09-28       Impact factor: 94.444

4.  Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.

Authors:  Rasmus Siersbæk; Ronni Nielsen; Sam John; Myong-Hee Sung; Songjoon Baek; Anne Loft; Gordon L Hager; Susanne Mandrup
Journal:  EMBO J       Date:  2011-03-22       Impact factor: 11.598

5.  Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart.

Authors:  Aibin He; Sek Won Kong; Qing Ma; William T Pu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-17       Impact factor: 11.205

6.  Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

Authors:  Michael Boergesen; Thomas Åskov Pedersen; Barbara Gross; Simon J van Heeringen; Dik Hagenbeek; Christian Bindesbøll; Sandrine Caron; Fanny Lalloyer; Knut R Steffensen; Hilde I Nebb; Jan-Åke Gustafsson; Hendrik G Stunnenberg; Bart Staels; Susanne Mandrup
Journal:  Mol Cell Biol       Date:  2011-12-12       Impact factor: 4.272

7.  Species-specific strategies underlying conserved functions of metabolic transcription factors.

Authors:  Raymond E Soccio; Geetu Tuteja; Logan J Everett; Zhaoyu Li; Mitchell A Lazar; Klaus H Kaestner
Journal:  Mol Endocrinol       Date:  2011-02-03

8.  Comparative epigenomic analysis of murine and human adipogenesis.

Authors:  Tarjei S Mikkelsen; Zhao Xu; Xiaolan Zhang; Li Wang; Jeffrey M Gimble; Eric S Lander; Evan D Rosen
Journal:  Cell       Date:  2010-10-01       Impact factor: 41.582

9.  Cross species comparison of C/EBPα and PPARγ profiles in mouse and human adipocytes reveals interdependent retention of binding sites.

Authors:  Søren F Schmidt; Mette Jørgensen; Yun Chen; Ronni Nielsen; Albin Sandelin; Susanne Mandrup
Journal:  BMC Genomics       Date:  2011-03-16       Impact factor: 3.969

10.  Conservation of transcription factor binding events predicts gene expression across species.

Authors:  Martin Hemberg; Gabriel Kreiman
Journal:  Nucleic Acids Res       Date:  2011-05-26       Impact factor: 16.971
View more
  4 in total

Review 1.  PPARγ and the global map of adipogenesis and beyond.

Authors:  Martina I Lefterova; Anders K Haakonsson; Mitchell A Lazar; Susanne Mandrup
Journal:  Trends Endocrinol Metab       Date:  2014-04-29       Impact factor: 12.015

Review 2.  PPARγ signaling and metabolism: the good, the bad and the future.

Authors:  Maryam Ahmadian; Jae Myoung Suh; Nasun Hah; Christopher Liddle; Annette R Atkins; Michael Downes; Ronald M Evans
Journal:  Nat Med       Date:  2013-05-07       Impact factor: 53.440

3.  PPARγ phase separates with RXRα at PPREs to regulate target gene expression.

Authors:  Zhean Li; Lingling Luo; Wenxia Yu; Ping Li; Danfeng Ou; Jia Liu; Hanhui Ma; Qinhu Sun; Aibin Liang; Cheng Huang; Tian Chi; Xingxu Huang; Yu Zhang
Journal:  Cell Discov       Date:  2022-04-26       Impact factor: 38.079

Review 4.  Meta-analysis and Consolidation of Farnesoid X Receptor Chromatin Immunoprecipitation Sequencing Data Across Different Species and Conditions.

Authors:  Emilian Jungwirth; Katrin Panzitt; Hanns-Ulrich Marschall; Gerhard G Thallinger; Martin Wagner
Journal:  Hepatol Commun       Date:  2021-07-01
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.