Literature DB >> 22455669

Palladium-catalyzed direct C-H bond alkynylations of heteroarenes using gem-dichloroalkenes.

Lutz Ackermann1, Christoph Kornhaass, Yingjun Zhu.   

Abstract

Palladium-catalyzed direct alkynylations of heteroarenes were accomplished with inexpensive gem-dichloroalkenes as user-friendly electrophiles, which set the stage for a modular, step-economical synthesis of diversely decorated heteroaryl alkynes with ample scope.

Entities:  

Year:  2012        PMID： 22455669     DOI： 10.1021/ol300514d

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Oxazoles for click chemistry II: synthesis of extended heterocyclic scaffolds.

Authors:  Pravin C Patil; Frederick A Luzzio; Donald R Demuth
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

2.  Directing group assisted rhodium catalyzed meta-C-H alkynylation of arenes.

Authors:  Sheuli Sasmal; Gaurav Prakash; Uttam Dutta; Ranjini Laskar; Goutam Kumar Lahiri; Debabrata Maiti
Journal:  Chem Sci       Date:  2022-04-20       Impact factor: 9.969

3.  Synthesis of (diarylmethyl)amines using Ni-catalyzed arylation of C(sp3)-H bonds.

Authors:  José A Fernández-Salas; Enrico Marelli; Steven P Nolan
Journal:  Chem Sci       Date:  2015-06-22       Impact factor: 9.825

4.  Unexpected Vulnerability of DPEphos to C-O Activation in the Presence of Nucleophilic Metal Hydrides.

Authors:  Mateusz K Cybulski; Nicholas A Beattie; Stuart A Macgregor; Mary F Mahon; Michael K Whittlesey
Journal:  Chemistry       Date:  2020-07-28       Impact factor: 5.236

5.  Unexpected rearrangements and a novel synthesis of 1,1-dichloro-1-alkenones from 1,1,1-trifluoroalkanones with aluminium trichloride.

Authors:  Beatrice Lansbergen; Catherine S Meister; Michael C McLeod
Journal:  Beilstein J Org Chem       Date:  2021-02-10       Impact factor: 2.883

6.  Nickel(ii)-catalyzed tandem C(sp2)-H bond activation and annulation of arenes with gem-dibromoalkenes.

Authors:  Yun Shi; Meng-Sheng Li; Fangdong Zhang; Baohua Chen
Journal:  RSC Adv       Date:  2018-08-13       Impact factor: 3.361

7.  Gold-catalyzed tandem reactions of amide-aldehyde-alkyne coupling and cyclization-synthesis of 2,4,5-trisubstituted oxazoles.

Authors:  Pierre Querard; Simon A Girard; Nick Uhlig; Chao-Jun Li
Journal:  Chem Sci       Date:  2015-10-06       Impact factor: 9.825
  7 in total

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