Literature DB >> 22454133

Managing patients with COPD exacerbation: does age matter?

Robert A Stone1, Derek Lowe, Jonathan M Potter, Rhona J Buckingham, C Michael Roberts, Nancy J Pursey.   

Abstract

INTRODUCTION: there is little information about the relationship between age and management of COPD exacerbation (AECOPD), although older persons are known to be at a greater risk of hospital admission.
METHODS: we have investigated responses from the clinical and patient questionnaire elements of the 2008 UK COPD audit, splitting the data into age decile.
RESULTS: age ranged from 27 to 102. Patient-reported data suggested older patients had inferior knowledge of COPD, undertook less self-care and were less likely to recognise symptoms of exacerbation prior to hospitalisation. Clinician-reported data showed that although older patients had severe disease and symptoms, greater co-morbidity at presentation and higher mortality, fewer were seen in hospital or followed up subsequently by respiratory specialists. Older patients were more likely to have a DNR order signed within 24 h of admission, irrespective of co-morbidities or performance status. The observations were particularly applicable to those aged 80 or above.
CONCLUSIONS: clinicians should consider increasing age as a specific risk factor in the management of COPD. Acute units and community teams should review carefully their protocols and pathways for how they assess, manage, discharge and follow-up older patients with COPD exacerbation.

Entities:  

Mesh:

Year:  2012        PMID: 22454133     DOI: 10.1093/ageing/afs039

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  9 in total

1.  [Stress and optimal ageing].

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Journal:  Z Gerontol Geriatr       Date:  2015-07-25       Impact factor: 1.281

2.  Development and Validation of a Multivariable Prediction Model to Identify Acute Exacerbation of COPD and Its Severity for COPD Management in China (DETECT Study): A Multicenter, Observational, Cross-Sectional Study.

Authors:  Yan Yin; Jinfu Xu; Shaoxi Cai; Yahong Chen; Yan Chen; Manxiang Li; Zhiqiang Zhang; Jian Kang
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2022-09-05

3.  Predictors of one-year mortality after hospitalization for an exacerbation of COPD.

Authors:  Cristóbal Esteban; Ady Castro-Acosta; Carlos Jose Alvarez-Martínez; Alberto Capelastegui; José Luis López-Campos; Francisco Pozo-Rodriguez
Journal:  BMC Pulm Med       Date:  2018-01-25       Impact factor: 3.317

4.  Prediction of short term re-exacerbation in patients with acute exacerbation of chronic obstructive pulmonary disease.

Authors:  Dong Liu; Shao-Hua Peng; Jing Zhang; Si-Hong Bai; Hai-Xia Liu; Jie-Ming Qu
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2015-07-02

5.  Does chronic obstructive pulmonary disease increase the risk of prostate cancer? A nationwide population-based study.

Authors:  Wen-Lin Hsu; Hung-Yi Chen; Fung-Wei Chang; Ren-Jun Hsu
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2019-08-22

6.  Influence of age on real-life effects of doxycycline for acute exacerbations among COPD outpatients: a population-based cohort study.

Authors:  Yuanyuan Wang; Jens H Bos; H Marike Boezen; Jan-Willem C Alffenaar; J F M van Boven; Catharina C M Schuiling-Veninga; Bob Wilffert; Eelko Hak
Journal:  BMJ Open Respir Res       Date:  2020-02

7.  Prognostic value of lymphocyte count for in-hospital mortality in patients with severe AECOPD.

Authors:  Yanlu Hu; Huanyu Long; Yang Cao; Yanfei Guo
Journal:  BMC Pulm Med       Date:  2022-10-05       Impact factor: 3.320

8.  Comparison of Immediate and Sequential Withdrawal of a Systemic Glucocorticoid in the Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Parallel-Controlled, Open-Label Study.

Authors:  Ling Zhou; Yuanyuan Fang; Wei Liu; Jianchu Zhang; Yingnan Wang; Sheng Xie; Minhua Zhong; Zhengyan Wang; Guangcai Li; Hongyan Ai; Hongrong Guo; Fanjun Zeng; Wei Xiao; Chenghong Li; Yi Hu; Yijun Tang; Huiguo Liu
Journal:  Front Mol Biosci       Date:  2021-05-20

9.  Prognostic indicators for in-hospital mortality in COPD with acute exacerbation in Thailand: a retrospective cohort study.

Authors:  Thotsaporn Morasert; Methus Jantarapootirat; Phichayut Phinyo; Jayanton Patumanond
Journal:  BMJ Open Respir Res       Date:  2020-05
  9 in total

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