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Literature DB >> 22454041

Wnt/beta-catenin signaling in glioma.

Kailiang Zhang¹, Junxia Zhang, Lei Han, Peiyu Pu, Chunsheng Kang.

Abstract

Extensive data have shown that Wnt/beta-catenin signaling is associated with various disease pathologies, including an important role in tumorigenesis. Here, we review the regulation of Wnt/beta-catenin signaling in glioma, with particular focus on the expression signatures of the main components in Wnt/beta-catenin signaling, the role of key factors in Wnt/beta-catenin signaling, and crosstalk with other signaling pathways. Finally, we discuss the involvement of microRNAs in Wnt/beta-catenin signaling in glioma. This review reveals new insights into the role of Wnt/beta-catenin signaling in gliomagenesis, and highlights new therapeutic approaches for glioma, based on the modulation of the Wnt/beta-catenin pathway.

Entities: Disease Gene

Mesh：

Substances：

Year: 2012 PMID： 22454041 DOI： 10.1007/s11481-012-9359-y

Source DB: PubMed Journal: J Neuroimmune Pharmacol ISSN： 1557-1890 Impact factor: 4.147

116 in total

1. Ligand receptor interactions in the Wnt signaling pathway in Drosophila.

Authors: Chi-hwa Wu; Roel Nusse
Journal: J Biol Chem Date: 2002-08-29 Impact factor: 5.157

Review 2. Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer.

Authors: M Leushacke; N Barker
Journal: Oncogene Date: 2011-10-17 Impact factor: 9.867

3. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.

Authors: Curtis A Thorne; Alison J Hanson; Judsen Schneider; Emilios Tahinci; Darren Orton; Christopher S Cselenyi; Kristin K Jernigan; Kelly C Meyers; Brian I Hang; Alex G Waterson; Kwangho Kim; Bruce Melancon; Victor P Ghidu; Gary A Sulikowski; Bonnie LaFleur; Adrian Salic; Laura A Lee; David M Miller; Ethan Lee
Journal: Nat Chem Biol Date: 2010-10-03 Impact factor: 15.040

4. Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells.

Authors: W Roth; C Wild-Bode; M Platten; C Grimmel; H S Melkonyan; J Dichgans; M Weller
Journal: Oncogene Date: 2000-08-31 Impact factor: 9.867

5. The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo.

Authors: Peng Xu; Mingzhe Qiu; Zhiyong Zhang; Chunsheng Kang; Rongcai Jiang; Zhifan Jia; Guangxiu Wang; Hao Jiang; Peiyu Pu
Journal: J Neurooncol Date: 2009-09-22 Impact factor: 4.130

6. Axin induces cell death and reduces cell proliferation in astrocytoma by activating the p53 pathway.

Authors: Li-Ying Zhang; Jing Ye; Feng Zhang; Fan-Fan Li; Hang Li; Yu Gu; Fang Liu; Guang-Sheng Chen; Qing Li
Journal: Int J Oncol Date: 2009-07 Impact factor: 5.650

7. A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected].

Authors: Katayoon H Emami; Cu Nguyen; Hong Ma; Dae Hoon Kim; Kwang Won Jeong; Masakatsu Eguchi; Randall T Moon; Jia-Ling Teo; Se Woong Oh; Hak Yeop Kim; Sung Hwan Moon; Jong Ryul Ha; Michael Kahn
Journal: Proc Natl Acad Sci U S A Date: 2004-08-16 Impact factor: 11.205

8. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.

Authors: Roger Stupp; Monika E Hegi; Warren P Mason; Martin J van den Bent; Martin J B Taphoorn; Robert C Janzer; Samuel K Ludwin; Anouk Allgeier; Barbara Fisher; Karl Belanger; Peter Hau; Alba A Brandes; Johanna Gijtenbeek; Christine Marosi; Charles J Vecht; Karima Mokhtari; Pieter Wesseling; Salvador Villa; Elizabeth Eisenhauer; Thierry Gorlia; Michael Weller; Denis Lacombe; J Gregory Cairncross; René-Olivier Mirimanoff
Journal: Lancet Oncol Date: 2009-03-09 Impact factor: 41.316

9. E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcription.

Authors: Vicente A Torres; Julio C Tapia; Diego A Rodriguez; Alvaro Lladser; Cristian Arredondo; Lisette Leyton; Andrew F G Quest
Journal: Mol Cell Biol Date: 2007-09-04 Impact factor: 4.272

10. Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.

Authors: I Dominguez; K Itoh; S Y Sokol
Journal: Proc Natl Acad Sci U S A Date: 1995-08-29 Impact factor: 11.205

55 in total

1. Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells.

Authors: Ulf D Kahlert; Menglin Cheng; Katharina Koch; Luigi Marchionni; Xing Fan; Eric H Raabe; Jarek Maciaczyk; Kristine Glunde; Charles G Eberhart
Journal: Int J Cancer Date: 2015-10-13 Impact factor: 7.396

2. MSX1 inhibits cell migration and invasion through regulating the Wnt/β-catenin pathway in glioblastoma.

Authors: Haiquan Tao; Li Guo; Lifeng Chen; Guangyu Qiao; Xianghui Meng; Bainan Xu; Wei Ye
Journal: Tumour Biol Date: 2015-08-15

3. MicroRNA miR-1249 downregulates adenomatous polyposis coli 2 expression and promotes glioma cells proliferation.

Authors: Baojun Fang; Guoliang Li; Chongfu Xu; Yuzuo Hui; Gang Li
Journal: Am J Transl Res Date: 2018-05-15 Impact factor: 4.060

Review 4. Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior.

Authors: Syed Mohammed Qasim Hussaini; Chan-Il Choi; Chang Hoon Cho; Hyo Jin Kim; Heechul Jun; Mi-Hyeon Jang
Journal: Neurosci Biobehav Rev Date: 2014-09-28 Impact factor: 8.989

Review 5. Thermodynamics in Neurodegenerative Diseases: Interplay Between Canonical WNT/Beta-Catenin Pathway-PPAR Gamma, Energy Metabolism and Circadian Rhythms.

Authors: Alexandre Vallée; Yves Lecarpentier; Rémy Guillevin; Jean-Noël Vallée
Journal: Neuromolecular Med Date: 2018-03-23 Impact factor: 3.843