Literature DB >> 22453963

The biology of protein kinase C.

Lily Zeng1, Samuel V Webster, Philip M Newton.   

Abstract

This review gives a basic introduction to the biology of protein kinase C, one of the first calcium-dependent kinases to be discovered. We review the structure and function of protein kinase C, along with some of the substrates of individual isoforms. We then review strategies for inhibiting PKC in experimental systems and finally discuss the therapeutic potential of targeting PKC. Each aspect is covered in summary, with links to detailed resources where appropriate.

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Year:  2012        PMID： 22453963     DOI： 10.1007/978-94-007-2888-2_28

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  30 in total

Review 1.  Regulation of paracellular permeability: factors and mechanisms.

Authors:  Yan-Jun Hu; Yi-Dong Wang; Fu-Qing Tan; Wan-Xi Yang
Journal:  Mol Biol Rep       Date:  2013-09-24       Impact factor: 2.316

2.  Heterologous, PKC-Mediated Desensitization of Human Histamine H3 Receptors Expressed in CHO-K1 Cells.

Authors:  Wilber Montejo-López; Nayeli Rivera-Ramírez; Juan Escamilla-Sánchez; Ubaldo García-Hernández; José-Antonio Arias-Montaño
Journal:  Neurochem Res       Date:  2016-06-27       Impact factor: 3.996

3.  2,4,6-Tribromophenol Exposure Decreases P-glycoprotein Transport at the Blood-Brain Barrier.

Authors:  Andrew W Trexler; Gabriel A Knudsen; Sascha C T Nicklisch; Linda S Birnbaum; Ronald E Cannon
Journal:  Toxicol Sci       Date:  2019-07-31       Impact factor: 4.849

4.  Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons.

Authors:  Maria C Velásquez-Martínez; Rafael Vázquez-Torres; Legier V Rojas; Priscila Sanabria; Carlos A Jiménez-Rivera
Journal:  Neuropharmacology       Date:  2014-09-28       Impact factor: 5.250

Review 5.  Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate.

Authors:  Senena Corbalán-García; Juan C Gómez-Fernández
Journal:  Biophys Rev       Date:  2013-11-27

6.  Global Gene Expression Analysis in PKCα-/- Mouse Skin Reveals Structural Changes in the Dermis and Defective Wound Granulation Tissue.

Authors:  Nichola H Cooper; Jeya P Balachandra; Matthew J Hardman
Journal:  J Invest Dermatol       Date:  2015-09-09       Impact factor: 8.551

Review 7.  Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters.

Authors:  Daniel P Bermingham; Randy D Blakely
Journal:  Pharmacol Rev       Date:  2016-10       Impact factor: 25.468

8.  The role of HSP27 in RACK1-mediated PKC activation in THP-1 cells.

Authors:  Emanuela Corsini; Valentina Galbiati; Angela Papale; Elena Kummer; Antonella Pinto; Antonio Guaita; Marco Racchi
Journal:  Immunol Res       Date:  2016-08       Impact factor: 2.829

Review 9.  Spinal and afferent PKC signaling mechanisms that mediate chronic pain in sickle cell disease.

Authors:  Ying He; Zaijie Jim Wang
Journal:  Neurosci Lett       Date:  2019-04-30       Impact factor: 3.046

10.  Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core.

Authors:  Brian P Ziemba; Joseph J Falke
Journal:  Chem Phys Lipids       Date:  2013-05-20       Impact factor: 3.329
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