Literature DB >> 22453468

Photonic-crystal membranes for optical detection of single nano-particles, designed for biosensor application.

Jon Olav Grepstad1, Peter Kaspar, Olav Solgaard, Ib-Rune Johansen, Aasmund S Sudbø.   

Abstract

A sensor designed to detect bio-molecules is presented. The sensor exploits a planar 2D photonic crystal (PC) membrane with sub-micron thickness and through holes, to induce high optical fields that allow detection of nano-particles smaller than the diffraction limit of an optical microscope. We report on our design and fabrication of a PC membrane with a nano-particle trapped inside. We have also designed and built an imaging system where an optical microscope and a CCD camera are used to take images of the PC membrane. Results show how the trapped nano-particle appears as a bright spot in the image. In a first experimental realization of the imaging system, single particles with a radius of 75 nm can be detected.

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Year:  2012        PMID: 22453468     DOI: 10.1364/OE.20.007954

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  8 in total

1.  Label-free detection with high-Q microcavities: a review of biosensing mechanisms for integrated devices.

Authors:  Frank Vollmer; Lan Yang
Journal:  Nanophotonics       Date:  2012-12-06       Impact factor: 8.449

Review 2.  Two-dimensional photonic crystals for sensitive microscale chemical and biochemical sensing.

Authors:  James E Baker; Rashmi Sriram; Benjamin L Miller
Journal:  Lab Chip       Date:  2015-02-21       Impact factor: 6.799

Review 3.  Photonic crystals: emerging biosensors and their promise for point-of-care applications.

Authors:  Hakan Inan; Muhammet Poyraz; Fatih Inci; Mark A Lifson; Murat Baday; Brian T Cunningham; Utkan Demirci
Journal:  Chem Soc Rev       Date:  2017-01-23       Impact factor: 54.564

4.  Spatial Resolution and Refractive Index Contrast of Resonant Photonic Crystal Surfaces for Biosensing.

Authors:  G J Triggs; M Fischer; D Stellinga; M G Scullion; G J O Evans; T F Krauss
Journal:  IEEE Photonics J       Date:  2015-06-01       Impact factor: 2.443

5.  Democratization of Nanoscale Imaging and Sensing Tools Using Photonics.

Authors:  Euan McLeod; Qingshan Wei; Aydogan Ozcan
Journal:  Anal Chem       Date:  2015-06-24       Impact factor: 6.986

6.  Multiplexed Simultaneous High Sensitivity Sensors with High-Order Mode Based on the Integration of Photonic Crystal 1 × 3 Beam Splitter and Three Different Single-Slot PCNCs.

Authors:  Jian Zhou; Lijun Huang; Zhongyuan Fu; Fujun Sun; Huiping Tian
Journal:  Sensors (Basel)       Date:  2016-07-07       Impact factor: 3.576

Review 7.  Slotted photonic crystal sensors.

Authors:  Mark G Scullion; Thomas F Krauss; Andrea Di Falco
Journal:  Sensors (Basel)       Date:  2013-03-15       Impact factor: 3.576

Review 8.  Label-Free Biosensor Imaging on Photonic Crystal Surfaces.

Authors:  Yue Zhuo; Brian T Cunningham
Journal:  Sensors (Basel)       Date:  2015-08-28       Impact factor: 3.576

  8 in total

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