Literature DB >> 22453170

Global Alzheimer Research Summit: basic and clinical research: present and future Alzheimer research.

Danielle Gonsalves1, Katarina Jovanovic, Bianca Da Costa Dias, Stefan F T Weiss.   

Abstract

We report here on the proceedings of the Global Alzheimer Summit that took place September 22-23, 2011 in Madrid, Spain. As Alzheimer disease (AD) is the leading cause of neurodegeneration in elderly individuals and as yet has no effective therapeutic option, it continues to stimulate global research interests. At the conference, leaders in the field of AD research provided insights into current developments in various areas of research, namely molecular mechanisms, genetics, novel aspects of AD research and translational research. Emphasis was also placed on the importance of biomarkers in the diagnosis of AD and development of current therapeutic strategies.

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Year:  2012        PMID: 22453170      PMCID: PMC3338957          DOI: 10.4161/pri.6.1.18854

Source DB:  PubMed          Journal:  Prion        ISSN: 1933-6896            Impact factor:   3.931


  5 in total

Review 1.  Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor.

Authors:  Aadilah Omar; Katarina Jovanovic; Bianca Da Costa Dias; Danielle Gonsalves; Kiashanee Moodley; Robert Caveney; Vusi Mbazima; Stefan F T Weiss
Journal:  Expert Opin Ther Pat       Date:  2010-11-27       Impact factor: 6.674

Review 2.  Structural and mechanistic commonalities of amyloid-β and the prion protein.

Authors:  Bianca Da Costa Dias; Katarina Jovanovic; Danielle Gonsalves; Stefan F T Weiss
Journal:  Prion       Date:  2011-07-01       Impact factor: 3.931

3.  The case described by Alois Alzheimer in 1911. Historical and conceptual perspectives based on the clinical record and neurohistological sections.

Authors:  H J Möller; M B Graeber
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1998       Impact factor: 5.270

Review 4.  Tau-mediated neurodegeneration in Alzheimer's disease and related disorders.

Authors:  Carlo Ballatore; Virginia M-Y Lee; John Q Trojanowski
Journal:  Nat Rev Neurosci       Date:  2007-09       Impact factor: 34.870

Review 5.  Interactions between PrP(c) and other ligands with the 37-kDa/67-kDa laminin receptor.

Authors:  Vusi Mbazima; Bianca Da Costa Dias; Aadilah Omar; Katarina Jovanovic; Stefan F T Weiss
Journal:  Front Biosci (Landmark Ed)       Date:  2010-06-01
  5 in total
  3 in total

Review 1.  Binding between Prion Protein and Aβ Oligomers Contributes to the Pathogenesis of Alzheimer's Disease.

Authors:  Chang Kong; Hao Xie; Zhenxing Gao; Ming Shao; Huan Li; Run Shi; Lili Cai; Shanshan Gao; Taolei Sun; Chaoyang Li
Journal:  Virol Sin       Date:  2019-05-15       Impact factor: 4.327

2.  Anti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease.

Authors:  Katarina Jovanovic; Danielle Gonsalves; Bianca Da Costa Dias; Kiashanee Moodley; Uwe Reusch; Stefan Knackmuss; Clement Penny; Marc S Weinberg; Melvyn Little; Stefan F T Weiss
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379

3.  Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicity.

Authors:  Bianca Da Costa Dias; Katarina Jovanovic; Danielle Gonsalves; Kiashanee Moodley; Uwe Reusch; Stefan Knackmuss; Clement Penny; Marc S Weinberg; Melvyn Little; Stefan F T Weiss
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379

  3 in total

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