| Literature DB >> 22453093 |
Alexey A Lugovskoy1, Janice M Reichert2, Alain Beck3.
Abstract
The 7th European Antibody Congress (EAC), organized by Terrapin Ltd., was again held in Geneva, Switzerland, following on the tradition established with the 4th EAC. The 2011 version of the EAC was attended by nearly 250 delegates who learned of the latest advances and trends in the global development of antibody-based therapeutics. The first day focused on advances in understanding structure-function relationships, choosing the best format, glycoengineering biobetter antibodies, improving the efficacy and drugability of mAbs and epitope mapping. On the second day, the discovery of novel targets for mAb therapy, clinical pipeline updates, use of antibody combinations to address resistance, generation and identification of mAbs against new targets and biosimilar mAb development were discussed. Antibody-drug conjugates, domain antibodies and new scaffolds and bispecific antibodies were the topics of the third day. In total, nearly 50 speakers provided updates of programs related to antibody research and development on-going in the academic, government and commercial sectors.Entities:
Keywords: antibody-drug conjugates; biosimilar antibodies; bispecific antibodies; protein scaffolds; therapeutic antibodies
Mesh:
Substances:
Year: 2012 PMID: 22453093 PMCID: PMC3361652 DOI: 10.4161/mabs.4.2.19426
Source DB: PubMed Journal: MAbs ISSN: 1942-0862 Impact factor: 5.857