Literature DB >> 22452730

Implication of conjugated linoleic acid (CLA) in human health.

Allison Dilzer1, Yeonhwa Park.   

Abstract

Conjugated linoleic acid (CLA) has drawn significant attention in the last two decades for its variety of biologically beneficial effects. CLA reduces body fat, cardiovascular diseases and cancer, and modulates immune and inflammatory responses as well as improves bone mass. It has been suggested that the overall effects of CLA are the results of interactions between two major isomers, cis-9,trans-11 and trans-10,cis-12. This review will primarily focus on current CLA publications involving humans, which are also summarized in the tables. Along with a number of beneficial effects of CLA, there are safety considerations for CLA supplementation in humans, which include effects on liver functions, milk fat depression, glucose metabolism, and oxidative stresses.

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Year:  2012        PMID： 22452730     DOI： 10.1080/10408398.2010.501409

Source DB:  PubMed          Journal:  Crit Rev Food Sci Nutr        ISSN： 1040-8398            Impact factor:   11.176


  63 in total

1.  Anti-allergic effect of the naturally-occurring conjugated linolenic acid isomer, jacaric acid, on the activated human mast cell line-1.

Authors:  Wai Nam Liu; Kwok Nam Leung
Journal:  Biomed Rep       Date:  2015-09-24

2.  c9, t11- conjugated linoleic acid induces HCC cell apoptosis and correlation with PPAR-γ signaling pathway.

Authors:  Guozhong Lu; Guoqing Zhang; Xing Zheng; Yan Zeng; Ziqi Xu; Weichi Zeng; Kebing Wang
Journal:  Am J Transl Res       Date:  2015-12-15       Impact factor: 4.060

3.  Conjugated linoleic acid (CLA) stimulates mitochondrial biogenesis signaling by the upregulation of PPARγ coactivator 1α (PGC-1α) in C2C12 cells.

Authors:  Yoo Kim; Yeonhwa Park
Journal:  Lipids       Date:  2015-02-27       Impact factor: 1.880

Review 4.  Reduced-fat foods: the complex science of developing diet-based strategies for tackling overweight and obesity.

Authors:  David J McClements
Journal:  Adv Nutr       Date:  2015-05-15       Impact factor: 8.701

5.  Quality evaluation of peony seed oil spray-dried in different combinations of wall materials during encapsulation and storage.

Authors:  Yan Shi; Shu-Jie Wang; Zong-Cai Tu; Hui Wang; Ru-Yi Li; Lu Zhang; Tao Huang; Ting Su; Cui Li
Journal:  J Food Sci Technol       Date:  2016-06-21       Impact factor: 2.701

6.  Conjugated linoleic Acid prevents ovariectomy-induced bone loss in mice by modulating both osteoclastogenesis and osteoblastogenesis.

Authors:  Md Mizanur Rahman; Gabriel Fernandes; Paul Williams
Journal:  Lipids       Date:  2013-12-13       Impact factor: 1.880

Review 7.  Impact of Conjugated Linoleic Acid (CLA) on Skeletal Muscle Metabolism.

Authors:  Yoo Kim; Jonggun Kim; Kwang-Youn Whang; Yeonhwa Park
Journal:  Lipids       Date:  2016-01-04       Impact factor: 1.880

8.  UV Lamp as a Facile Ozone Source for Structural Analysis of Unsaturated Lipids Via Electrospray Ionization-Mass Spectrometry.

Authors:  Craig A Stinson; Wenpeng Zhang; Yu Xia
Journal:  J Am Soc Mass Spectrom       Date:  2017-12-12       Impact factor: 3.109

9.  Types of oilseed and adipose tissue influence the composition and relationships of polyunsaturated fatty acid biohydrogenation products in steers fed a grass hay diet.

Authors:  C Mapiye; J L Aalhus; T D Turner; D C Rolland; J A Basarab; V S Baron; T A McAllister; H C Block; S D Proctor; M E R Dugan
Journal:  Lipids       Date:  2014-01-08       Impact factor: 1.880

10.  trans-10,cis-12 CLA promotes osteoblastogenesis via SMAD mediated mechanism in bone marrow mesenchymal stem cells.

Authors:  Jonggun Kim; Yooheon Park; Yeonhwa Park
Journal:  J Funct Foods       Date:  2014-05-01       Impact factor: 4.451
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