Saleh A Alqahtani1. 1. Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. Saleh.Alqahtani@utsouthwestern.edu
Abstract
PURPOSE OF REVIEW: Successful transplant outcomes require optimal patient selection and timing. This review will update clinicians with current status and challenges in liver transplantation. Currently, the major limitation facing liver transplant centers is the shortage of organs. The limited availability of organs has led to long waiting periods for liver transplantation and consequently many patients become seriously ill or die while on the waiting list. RECENT FINDINGS: This has major implications in the selection of patients, as well as the timing of transplant, for optimal use of these scarce organs. Indications and contraindications have changed slightly over the years and will be reviewed in this article. SUMMARY: Timing for transplantation has changed more dramatically in the recent years because major changes to organ allocation systems have been undertaken to provide clinicians with a better way to prioritize patients for liver transplant.
PURPOSE OF REVIEW: Successful transplant outcomes require optimal patient selection and timing. This review will update clinicians with current status and challenges in liver transplantation. Currently, the major limitation facing liver transplant centers is the shortage of organs. The limited availability of organs has led to long waiting periods for liver transplantation and consequently many patients become seriously ill or die while on the waiting list. RECENT FINDINGS: This has major implications in the selection of patients, as well as the timing of transplant, for optimal use of these scarce organs. Indications and contraindications have changed slightly over the years and will be reviewed in this article. SUMMARY: Timing for transplantation has changed more dramatically in the recent years because major changes to organ allocation systems have been undertaken to provide clinicians with a better way to prioritize patients for liver transplant.
Authors: A Collin de l'Hortet; K Takeishi; J Guzman-Lepe; K Handa; K Matsubara; K Fukumitsu; K Dorko; S C Presnell; H Yagi; A Soto-Gutierrez Journal: Am J Transplant Date: 2016-02-18 Impact factor: 8.086
Authors: Marek Saracyn; Marek Brytan; Robert Zdanowski; Tomasz Ząbkowski; Przemysław Dyrla; Janusz Patera; Stanisław Wojtuń; Wojciech Kozłowski; Zofia Wańkowicz Journal: World J Gastroenterol Date: 2014-12-14 Impact factor: 5.742
Authors: Keunhee Oh; Suh Youn Shon; Myung Won Seo; Hak Mo Lee; Ju-Eun Oh; Eun Young Choi; Dong-Sup Lee; Kyong Soo Park Journal: Exp Mol Med Date: 2015-10-02 Impact factor: 8.718