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Literature DB >> 22450755

A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue.

Na Young Baek¹, Cheol Ho Heo, Chang Su Lim, Goutam Masanta, Bong Rae Cho, Hwan Myung Kim.

Abstract

We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn(2+) and can selectively detect mitochondrial Zn(2+) in a rat hippocampal slice at a depth of 100-200 μm by using two-photon microscopy. This journal is © The Royal Society of Chemistry 2012

Entities: Chemical Species

Mesh：

Substances：
Fluorescent Dyes
Ions
Zinc

Year: 2012 PMID： 22450755 DOI： 10.1039/c2cc31077e

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

12 in total

Review 1. Small-molecule fluorophores and fluorescent probes for bioimaging.

Authors: Takuya Terai; Tetsuo Nagano
Journal: Pflugers Arch Date: 2013-02-15 Impact factor: 3.657

2. Arduino Due based tool to facilitate in vivo two-photon excitation microscopy.

Authors: Pietro Artoni; Silvia Landi; Sebastian Sulis Sato; Stefano Luin; Gian Michele Ratto
Journal: Biomed Opt Express Date: 2016-03-30 Impact factor: 3.732

3. Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells.

Authors: Shuwei Zhang; Rashmi Adhikari; Mingxi Fang; Nethaniah Dorh; Cong Li; Meghnath Jaishi; Jingtuo Zhang; Ashutosh Tiwari; Ranjit Pati; Fen-Tair Luo; Haiying Liu
Journal: ACS Sens Date: 2016-11-17 Impact factor: 7.711

4. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

Authors: Wen Chyan; Daniel Y Zhang; Stephen J Lippard; Robert J Radford
Journal: Proc Natl Acad Sci U S A Date: 2013-12-12 Impact factor: 11.205

9. Biologically targeted probes for Zn²⁺: a diversity oriented modular "click-S_NAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Authors: J Pancholi; D J Hodson; K Jobe; G A Rutter; S M Goldup; M Watkinson
Journal: Chem Sci Date: 2014-06-27 Impact factor: 9.825

Review 10. Subcellular localised small molecule fluorescent probes to image mobile Zn².

Authors: Le Fang; Michael Watkinson
Journal: Chem Sci Date: 2020-10-09 Impact factor: 9.825

A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue.

Review 1. Small-molecule fluorophores and fluorescent probes for bioimaging.

2. Arduino Due based tool to facilitate in vivo two-photon excitation microscopy.

3. Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells.

4. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

5. Sensing of Zn²⁺ ion by N-furfurylsalicylaldimine based on CHEF process.

6. A mitochondria-targeted ratiometric two-photon fluorescent probe for biological zinc ions detection.

Review 7. Two-photon probes for in vivo multicolor microscopy of the structure and signals of brain cells.

Review 8. Mitochondrial-targeted two-photon fluorescent probes for zinc ions, H2O2, and thiols in living tissues.

9. Biologically targeted probes for Zn²⁺: a diversity oriented modular "click-S_NAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Review 10. Subcellular localised small molecule fluorescent probes to image mobile Zn².

A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue.

Review 1. Small-molecule fluorophores and fluorescent probes for bioimaging.

2. Arduino Due based tool to facilitate in vivo two-photon excitation microscopy.

3. Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells.

4. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

5. Sensing of Zn²⁺ ion by N-furfurylsalicylaldimine based on CHEF process.

6. A mitochondria-targeted ratiometric two-photon fluorescent probe for biological zinc ions detection.

Review 7. Two-photon probes for in vivo multicolor microscopy of the structure and signals of brain cells.

Review 8. Mitochondrial-targeted two-photon fluorescent probes for zinc ions, H2O2, and thiols in living tissues.

9. Biologically targeted probes for Zn2+: a diversity oriented modular "click-SNAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Review 10. Subcellular localised small molecule fluorescent probes to image mobile Zn2.

9. Biologically targeted probes for Zn²⁺: a diversity oriented modular "click-S_NAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the ESI. See DOI: 10.1039/c4sc01249f.

Review 10. Subcellular localised small molecule fluorescent probes to image mobile Zn².