Literature DB >> 22449960

From circuits to behavior: a bridge too far?

Matteo Carandini1.   

Abstract

Neuroscience seeks to understand how neural circuits lead to behavior. However, the gap between circuits and behavior is too wide. An intermediate level is one of neural computations, which occur in individual neurons and populations of neurons. Some computations seem to be canonical: repeated and combined in different ways across the brain. To understand neural computations, we must record from a myriad of neurons in multiple brain regions. Understanding computation guides research in the underlying circuits and provides a language for theories of behavior.

Mesh:

Year:  2012        PMID: 22449960     DOI: 10.1038/nn.3043

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN: 1097-6256            Impact factor:   24.884


  26 in total

1.  The middle way.

Authors:  R B Laughlin; D Pines; J Schmalian; B P Stojkovic; P Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

Review 2.  Receptive field structure in cortical area 3b of the alert monkey.

Authors:  James J DiCarlo; Kenneth O Johnson
Journal:  Behav Brain Res       Date:  2002-09-20       Impact factor: 3.332

Review 3.  New roles for synaptic inhibition in sound localization.

Authors:  Benedikt Grothe
Journal:  Nat Rev Neurosci       Date:  2003-07       Impact factor: 34.870

4.  The structure of the nervous system of the nematode Caenorhabditis elegans.

Authors:  J G White; E Southgate; J N Thomson; S Brenner
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1986-11-12       Impact factor: 6.237

Review 5.  The blue brain project.

Authors:  Henry Markram
Journal:  Nat Rev Neurosci       Date:  2006-02       Impact factor: 34.870

Review 6.  Inhibition, spike threshold, and stimulus selectivity in primary visual cortex.

Authors:  Nicholas J Priebe; David Ferster
Journal:  Neuron       Date:  2008-02-28       Impact factor: 17.173

7.  The seductive allure of neuroscience explanations.

Authors:  Deena Skolnick Weisberg; Frank C Keil; Joshua Goodstein; Elizabeth Rawson; Jeremy R Gray
Journal:  J Cogn Neurosci       Date:  2008-03       Impact factor: 3.225

8.  Influence of dendritic structure on firing pattern in model neocortical neurons.

Authors:  Z F Mainen; T J Sejnowski
Journal:  Nature       Date:  1996-07-25       Impact factor: 49.962

Review 9.  Computational neuroscience.

Authors:  T J Sejnowski; C Koch; P S Churchland
Journal:  Science       Date:  1988-09-09       Impact factor: 47.728

Review 10.  Normalization as a canonical neural computation.

Authors:  Matteo Carandini; David J Heeger
Journal:  Nat Rev Neurosci       Date:  2011-11-23       Impact factor: 34.870

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  69 in total

1.  The empirical characteristics of human pattern vision defy theoretically-driven expectations.

Authors:  Peter Neri
Journal:  PLoS Comput Biol       Date:  2018-12-04       Impact factor: 4.475

Review 2.  Genetically engineered fluorescent voltage reporters.

Authors:  Hiroki Mutoh; Walther Akemann; Thomas Knöpfel
Journal:  ACS Chem Neurosci       Date:  2012-06-06       Impact factor: 4.418

3.  Coordination of Orofacial Motor Actions into Exploratory Behavior by Rat.

Authors:  Anastasia Kurnikova; Jeffrey D Moore; Song-Mao Liao; Martin Deschênes; David Kleinfeld
Journal:  Curr Biol       Date:  2017-02-16       Impact factor: 10.834

Review 4.  Facing the challenge of mammalian neural microcircuits: taking a few breaths may help.

Authors:  Jack L Feldman; Kaiwen Kam
Journal:  J Physiol       Date:  2015-01-01       Impact factor: 5.182

5.  Theory of cortical function.

Authors:  David J Heeger
Journal:  Proc Natl Acad Sci U S A       Date:  2017-02-06       Impact factor: 11.205

Review 6.  Top-down models in biology: explanation and control of complex living systems above the molecular level.

Authors:  Giovanni Pezzulo; Michael Levin
Journal:  J R Soc Interface       Date:  2016-11       Impact factor: 4.118

7.  Syringe-injectable mesh electronics integrate seamlessly with minimal chronic immune response in the brain.

Authors:  Tao Zhou; Guosong Hong; Tian-Ming Fu; Xiao Yang; Thomas G Schuhmann; Robert D Viveros; Charles M Lieber
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-22       Impact factor: 11.205

8.  A plausible neural circuit for decision making and its formation based on reinforcement learning.

Authors:  Hui Wei; Dawei Dai; Yijie Bu
Journal:  Cogn Neurodyn       Date:  2017-02-18       Impact factor: 5.082

9.  Towards a computational(ist) neurobiology of language: Correlational, integrated, and explanatory neurolinguistics.

Authors:  David Embick; David Poeppel
Journal:  Lang Cogn Neurosci       Date:  2015-05-01       Impact factor: 2.331

10.  Model-based cognitive neuroscience.

Authors:  Thomas J Palmeri; Bradley C Love; Brandon M Turner
Journal:  J Math Psychol       Date:  2016-11-23       Impact factor: 2.223

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