Literature DB >> 22449071

Tec family kinases in inflammation and disease.

Nicole J Horwood1, Ania M Urbaniak, Lynett Danks.   

Abstract

Over the last decade, the Tec family of nonreceptor tyrosine kinases (Btk, Tec, Bmx, Itk, and Rlk) have been shown to play a key role in inflammation and bone destruction. Bruton's tyrosine kinase (Btk) has been the most widely studied due to the critical role of this kinase in B-cell development and recent evidence showing that blocking Btk signaling is effective in ameliorating lymphoma progression and experimental arthritis. This review will examine the role of TFK in myeloid cell function and the potential of targeting these kinases as a therapeutic intervention in autoimmune disorders such as rheumatoid arthritis.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22449071     DOI： 10.3109/08830185.2012.670334

Source DB:  PubMed          Journal:  Int Rev Immunol        ISSN： 0883-0185            Impact factor:   5.311


  29 in total

1.  Covalent Inhibitors of the TEC Family of Kinases and Their Methods of Use.

Authors:  Benjamin E Blass
Journal:  ACS Med Chem Lett       Date:  2018-05-14       Impact factor: 4.345

Review 2.  PI3Kβ-A Versatile Transducer for GPCR, RTK, and Small GTPase Signaling.

Authors:  Anne R Bresnick; Jonathan M Backer
Journal:  Endocrinology       Date:  2019-03-01       Impact factor: 4.736

3.  Effects of Tec Tyrosine Kinase Inhibition on the Inflammatory Response of Severe Acute Pancreatitis-Associated Acute Lung Injury in Mice.

Authors:  Yiteng Meng; Shuo Sha; Jing Yang; Hongbo Ren
Journal:  Dig Dis Sci       Date:  2019-02-14       Impact factor: 3.199

Review 4.  PI3K signaling in cancer: beyond AKT.

Authors:  Evan C Lien; Christian C Dibble; Alex Toker
Journal:  Curr Opin Cell Biol       Date:  2017-03-24       Impact factor: 8.382

5.  Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.

Authors:  Yiming Zhong; Shuai Dong; Ethan Strattan; Li Ren; Jonathan P Butchar; Kelsey Thornton; Anjali Mishra; Pierluigi Porcu; J Michael Bradshaw; Angelina Bisconte; Timothy D Owens; Erik Verner; Ken A Brameld; Jens Oliver Funk; Ronald J Hill; Amy J Johnson; Jason A Dubovsky
Journal:  J Biol Chem       Date:  2015-01-15       Impact factor: 5.157

6.  Sialidase neu4 deficiency is associated with neuroinflammation in mice.

Authors:  Zehra Kevser Timur; Orhan Kerim Inci; Secil Akyildiz Demir; Volkan Seyrantepe
Journal:  Glycoconj J       Date:  2021-10-23       Impact factor: 2.916

7.  Characterization of Altered Gene Expression and Histone Methylation in Peripheral Blood Mononuclear Cells Regulating Inflammation in COVID-19 Patients.

Authors:  Xiaoming Yang; Alex C Rutkovsky; Juhua Zhou; Yin Zhong; Julian Reese; Timothy Schnell; Helmut Albrecht; William B Owens; Prakash S Nagarkatti; Mitzi Nagarkatti
Journal:  J Immunol       Date:  2022-04-04       Impact factor: 5.426

8.  Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.

Authors:  Raji E Joseph; Iivari Kleino; Thomas E Wales; Qian Xie; D Bruce Fulton; John R Engen; Leslie J Berg; Amy H Andreotti
Journal:  Sci Signal       Date:  2013-08-27       Impact factor: 8.192

Review 9.  B-cell selection and the development of autoantibodies.

Authors:  Natalia V Giltiay; Craig P Chappell; Edward A Clark
Journal:  Arthritis Res Ther       Date:  2012-11-02       Impact factor: 5.156

10.  Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways: Src family kinases and Calcium.

Authors:  Chun-Yu Chen; Yann-Lii Leu; Yu Fang; Chwan-Fwu Lin; Liang-Mou Kuo; Wei-Che Sung; Yung-Fong Tsai; Pei-Jen Chung; Ming-Chung Lee; Yu-Ting Kuo; Hsuan-Wu Yang; Tsong-Long Hwang
Journal:  Sci Rep       Date:  2015-12-14       Impact factor: 4.379
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.