Literature DB >> 22446061

The structural and functional diversification of the Toxicofera reptile venom system.

Bryan G Fry1, Nicholas R Casewell, Wolfgang Wüster, Nicolas Vidal, Bruce Young, Timothy N W Jackson.   

Abstract

The evolutionary origin and diversification of the reptilian venom system is described. The resolution of higher-order molecular phylogenetics has clearly established that a venom system is ancestral to snakes. The diversification of the venom system within lizards is discussed, as is the role of venom delivery in the behavioural ecology of these taxa (particularly Varanus komodoensis). The more extensive diversification of the venom system in snakes is summarised, including its loss in some clades. Finally, we discuss the contentious issue of a definition for "venom", supporting an evolutionary definition that recognises the homology of both the venom delivery systems and the toxins themselves.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22446061     DOI: 10.1016/j.toxicon.2012.02.013

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  42 in total

Review 1.  Privileged frameworks from snake venom.

Authors:  T A Reeks; B G Fry; P F Alewood
Journal:  Cell Mol Life Sci       Date:  2015-02-19       Impact factor: 9.261

2.  Has snake fang evolution lost its bite? New insights from a structural mechanics viewpoint.

Authors:  Chris Broeckhoven; Anton du Plessis
Journal:  Biol Lett       Date:  2017-08       Impact factor: 3.703

3.  Widespread and Differential Neurotoxicity in Venoms from the Bitis Genus of Viperid Snakes.

Authors:  Nicholas J Youngman; Richard J Harris; Tam M Huynh; Kristian Coster; Eric Sundman; Ralph Braun; Arno Naude; Wayne C Hodgson; Bryan G Fry
Journal:  Neurotox Res       Date:  2021-01-11       Impact factor: 3.911

4.  Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraint.

Authors:  Eivind A B Undheim; Brett R Hamilton; Nyoman D Kurniawan; Greg Bowlay; Bronwen W Cribb; David J Merritt; Bryan G Fry; Glenn F King; Deon J Venter
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-16       Impact factor: 11.205

Review 5.  Why do we study animal toxins?

Authors:  Yun Zhang
Journal:  Dongwuxue Yanjiu       Date:  2015-07-18

6.  The Deep Origin and Recent Loss of Venom Toxin Genes in Rattlesnakes.

Authors:  Noah L Dowell; Matt W Giorgianni; Victoria A Kassner; Jane E Selegue; Elda E Sanchez; Sean B Carroll
Journal:  Curr Biol       Date:  2016-09-15       Impact factor: 10.834

Review 7.  Neuropeptide signalling systems - An underexplored target for venom drug discovery.

Authors:  Helen C Mendel; Quentin Kaas; Markus Muttenthaler
Journal:  Biochem Pharmacol       Date:  2020-06-30       Impact factor: 5.858

Review 8.  Cabinet of Curiosities: Venom Systems and Their Ecological Function in Mammals, with a Focus on Primates.

Authors:  Johanna E Rode-Margono; K Anne-Isola Nekaris
Journal:  Toxins (Basel)       Date:  2015-07-17       Impact factor: 4.546

9.  Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenalf.

Authors:  Kartik Sunagar; Bryan Grieg Fry; Timothy N W Jackson; Nicholas R Casewell; Eivind A B Undheim; Nicolas Vidal; Syed A Ali; Glenn F King; Karthikeyan Vasudevan; Vitor Vasconcelos; Agostinho Antunes
Journal:  PLoS One       Date:  2013-11-29       Impact factor: 3.240

10.  Integrated "omics" profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus.

Authors:  Jordi Durban; Alicia Pérez; Libia Sanz; Aarón Gómez; Fabián Bonilla; Santos Rodríguez; Danilo Chacón; Mahmood Sasa; Yamileth Angulo; José M Gutiérrez; Juan J Calvete
Journal:  BMC Genomics       Date:  2013-04-10       Impact factor: 3.969

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