Literature DB >> 22445089

Dermal and pulmonary absorption of ethanol from alcohol-based hand rub.

D Ahmed-Lecheheb1, L Cunat, P Hartemann, A Hautemanière.   

Abstract

BACKGROUND: Ethanol intoxication of healthcare workers (HCWs) using alcohol-based hand rubs (ABHRs) in the workplace is a potentially serious issue. This study quantified the level of ethanol absorption among HCWs after hygienic hand disinfection.
METHODS: Eighty-six HCWs from Nancy University Hospital were tested before and after a 4-h shift. Participants used ABHR containing 70% ethanol. Levels of ethanol, acetaldehyde and acetate in blood and urine were determined using gas chromatography. A breathalyzer was used to measure the level of ethanol in expired air.
RESULTS: Ethanol [mean concentration 0.076 (standard deviation 0.05) mg/L] was detected in the expired air of 28 HCWs 1-2 min post exposure. Ethanol, acetaldehyde and acetate were undetectable in blood after a 4-h shift, and urine tests were negative in all participants.
CONCLUSION: Ethanol exposure from ABHR, particularly inhalation of vapours, resulted in positive breathalyzer readings 1-2 min after exposure. Dermal absorption of ethanol was not detected. Pulmonary absorption was detected but was below toxic levels.
Copyright © 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22445089     DOI: 10.1016/j.jhin.2012.02.006

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  7 in total

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Review 4.  Biosurfactants in the sustainable eradication of SARS COV-2 from the environmental surfaces.

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5.  Preventing neonatal sepsis in rural Uganda: a cross-over study comparing the tolerance and acceptability of three alcohol-based hand rub formulations.

Authors:  J Ditai; M Mudoola; M Gladstone; J Abeso; J Dusabe-Richards; M Adengo; P Olupot-Olupot; E D Carrol; J Storr; A Medina-Lara; B Faragher; A D Weeks
Journal:  BMC Public Health       Date:  2018-11-20       Impact factor: 3.295

6.  "We have to clean ourselves to ensure that our children are healthy and beautiful": findings from a qualitative assessment of a hand hygiene poster in rural Uganda.

Authors:  B L Harrison; C Ogara; M Gladstone; E D Carrol; J Dusabe-Richards; A Medina-Lara; J Ditai; A D Weeks
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Review 7.  Sensitivity of SARS-CoV-2 towards Alcohols: Potential for Alcohol-Related Toxicity in Humans.

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  7 in total

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